SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley +1 more source
Peutz-Jeghers syndrome with concurrent lobular endocervical glandular hyperplasia and sex cord tumor with annular tubules: a case report. [PDF]
Yin M, Lu C, Cheng L.
europepmc +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Weight cycling and cancer risk in the Sister Study. [PDF]
Stevens VL +4 more
europepmc +1 more source
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao +11 more
wiley +1 more source
Impact of <i>IGF2BP2</i> genetic variants and expression levels with the progression of endometrial cancer. [PDF]
Kan CY +8 more
europepmc +1 more source
Environmental endocrine disruptors and endometrial cancer risk: a systematic review and meta-analysis of cadmium and polychlorinated biphenyls, with emerging evidence on PFAS, phthalates, and bisphenols. [PDF]
Gong L, Lu W, Zhao Y, Mei H, Zhang X.
europepmc +1 more source
Endometrial Cancer Recurrence Risk Following Robotic Hysterectomy. [PDF]
Zhu S +7 more
europepmc +1 more source
Hereditary cancer syndromes with gynecological cancer risk: focus on prevention strategies. [PDF]
Duranti S +8 more
europepmc +1 more source
Case Report: Hormone receptor-positive uterine mesonephric-like adenocarcinoma. [PDF]
Luo T, Shen J, Zeng Y, Xie K, Xu N.
europepmc +1 more source

