Results 221 to 230 of about 86,874 (288)

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Weight cycling and cancer risk in the Sister Study. [PDF]

open access: yesAm J Epidemiol
Stevens VL   +4 more
europepmc   +1 more source

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

open access: yesHistopathology, EarlyView.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao   +11 more
wiley   +1 more source

Impact of <i>IGF2BP2</i> genetic variants and expression levels with the progression of endometrial cancer. [PDF]

open access: yesInt J Med Sci
Kan CY   +8 more
europepmc   +1 more source

Endometrial Cancer Recurrence Risk Following Robotic Hysterectomy. [PDF]

open access: yesCurr Oncol
Zhu S   +7 more
europepmc   +1 more source

Hereditary cancer syndromes with gynecological cancer risk: focus on prevention strategies. [PDF]

open access: yesFront Oncol
Duranti S   +8 more
europepmc   +1 more source

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