Results 31 to 40 of about 9,262 (176)

A Case of Endometrial Stromal Sarcoma with Synchronous Bilateral Adenocarcinoma of Ovary

Case Reports in Obstetrics and Gynecology, 2012
Endometrial stromal tumor is a rare mesenchymal uterine tumor. We report the case of a patient with endometrial stromal sarcoma and concomitant bilateral endometrioid adenocarcinoma of the ovary in the context of pelvic endometriosis.
Olga Caramelo, Carol Marinho, Teresa Rebelo, Natália Amaral, Fernando Mota, Fernanda Xavier da Cunha, Isabel Torgal   +6 more
doaj   +1 more source

Endometrial Stromal Nodule: A Rarity and a Pathological Challenge

Case Reports in Obstetrics and Gynecology, 2015
Endometrial stromal tumors are rare, and endometrial stromal nodule is the least common. In the region of Middle Jutland, Denmark, only two cases are reported since 1995.
Camilla Skovvang Borg, Peter Humaidan, Hanne Noer, Huda Galib Majeed   +3 more
doaj   +1 more source

A remarkable response to pazopanib, despite recurrent liver toxicity, in a patient with a high grade endometrial stromal sarcoma, a case report

BMC Cancer, 2018
Background Pazopanib is an oral tyrosine kinase inhibitor registered for metastatic renal cell carcinoma and soft tissue sarcoma. Liver toxicity is a common side effect for this class of agents.
Arie J. Verschoor, Fabiënne A. R. M. Warmerdam, Tjalling Bosse, Judith V. M. G. Bovée, Hans Gelderblom   +4 more
doaj   +1 more source

Histopathology of Endometrial Stromal Sarcoma with Emphasis on Immunohistochemistry Marker Expression: Report of Three Cases

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Endometrial stromal tumors are rare uterine mesenchymal neoplasms. Endometrial stromal sarcomas (ESSs) are of endometrial stromal origin that accounts for approximately 1% of all uterine malignant neoplasms.
Narayanamoorthy Keerthyraj, Vigneswaramoorthi Vinayagamoorthi, Erli Amel Ivan, V Sriram, Govindasamy Revathi, Ramya Gandhi   +5 more
doaj   +1 more source

High-Grade Endometrial Stromal Sarcoma: Molecular Alterations and Potential Immunotherapeutic Strategies

Frontiers in Immunology, 2022
Endometrial stromal tumor (EST) is an uncommon and unusual mesenchymal tumor of the uterus characterized by multicolored histopathological, immunohistochemical, and molecular features. The morphology of ESTs is similar to normal endometrial stromal cells
Youngah Kim, Youngah Kim, Dohyang Kim, Woo Jung Sung, Jaewoo Hong   +4 more
doaj   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

International Journal of Cancer, EarlyView.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley, Liesbet J. Van Eycken, Meredith E. Giuliani, Brian A. Rous, Shao Hui Huang, Hisao Asamura, Mary K. Gospodarowicz, Anne W. Lee, Brian O'Sullivan   +8 more
wiley   +1 more source

A rare case report of high-grade endometrial stromal sarcoma in a seemingly healthy uterus of a young patient – Optimally managed by minimally access surgery

Indian Journal of Medical and Paediatric Oncology, 2019
Endometrial stromal sarcomas (ESSs) are a rare entity, constituting 10% of all uterine sarcomas and 0.2% of all uterine malignancies. We report a very rare case of high-grade endometrial stromal sarcoma in a 34-year-old female with fibroids uterus ...
Kanika Jain, Debasis Dutta, Kanika Chopra, Pallav Gupta   +3 more
doaj   +1 more source

Disseminated Endometriosis and Low-Grade Endometrioid Stromal Sarcoma in a Patient with a History of Uterine Morcellation for Adenomyosis

Case Reports in Obstetrics and Gynecology, 2020
Morcellation of benign uterine tumors allows for removal of the tumors via minimally invasive laparoscopic procedures. However, in rare cases, morcellation has been associated with upstaging of unexpected malignancies.
Daniel P. Stefanko, Ramez Eskander, Omonigho Aisagbonhi   +2 more
doaj   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

Med Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji, Da Zhong, Tian Rao, Xiaojun Li, Weiyu Kong, Xi Zhang, Xiyi Wei, Bing Yao, Xinqiang Li, Ninghong Song, Chao Qin   +10 more
wiley   +1 more source