Results 91 to 100 of about 56,095 (256)

Abordaje transdisciplinario del dolor pélvico crónico asociado a endometriosis en Colombia: declaración de consenso para una atención centrada en la paciente

Revista Colombiana de Obstetricia y Ginecología
Objetivo: esta declaración de consenso busca transformar la atención de la endometriosis en Colombia a través de la estandarización del manejo clínico mediante la conformación de equipos transdisciplinarios y el uso de indicadores de calidad, el ...
Juan Diego Villegas-Echeverri, Lilian Rubiano Paiva, Luis Fernando García Rodríguez, Jorge Darío López-Isanoa, José Fernando de los Ríos Posada, Jerutsa Orjuela Monsalve, Carolina Meza Paul, Claudia Bastidas Guarín, Álvaro José Escobar Flórez, Angélica Cuello Salcedo, Hebert Quintero, Daniel Sanabria, Juan Carlos Ramírez Mejía, Lina Grajales Marulanda, María Alejandra Santacruz Mosquera, Jimmy Castañeda Castañeda   +15 more
doaj   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Core stability in women with and without chronic pelvic pain

PM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin, Abhilasha Kumar, Michael Wesolowski, Laura Glaser, Colleen M. Fitzgerald, Stacey Bennis   +5 more
wiley   +1 more source

Endometriosis and autoimmunity

Autoimmunity Reviews
Endometriosis is a female-specific chronic condition that affects 1 in 10 women and other individuals with a uterus worldwide with common symptoms that include pelvic pain and infertility. Reliable and effective non-invasive biomarkers for endometriosis do not exist, and therefore currently a diagnosis of endometriosis requires direct visualization of ...
Blanco L. P., Salmeri N., Temkin S. M., Shanmugam V. K., Stratton P.   +4 more
openaire   +2 more sources

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Factors Associated With Hormone Replacement Therapy Use: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To identify factors associated with HRT uptake among women. Design A systematic review and meta‐analysis to identify factors associated with HRT uptake. Setting Retrospective and prospective cohort studies, case–control studies and cross‐sectional studies from any country and in any language. Population The study population was women
Wema Meranda Mtika, Deborah Allen, Eve Tranter, Grace Glover, Janice Hoang, Sarah Hillman, Carol Coupland, Julia Hippisley‐Cox, Lynn Tatnell, Jennifer A. Hirst   +9 more
wiley   +1 more source

Symptom Flares in Endometriosis: Burden, Self‐Management and Barriers to Care in a Cross‐Sectional Survey

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore the characteristics of symptom flares, individual experiences and behaviours during flares in people with endometriosis. Design Online questionnaire shared on patient support sites. Setting People with a confirmed or working diagnosis of endometriosis (a working diagnosis is given by clinicians based on symptoms/history ...
Lydia Coxon, Emma Evans, Francine Toye, Emma Cox, Katy Vincent   +4 more
wiley   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Evaluation of the IOTA ADNEX Model, Two‐Step Strategy and RMI in Routine Gynaecologic Care in Denmark and Implications for Implementation: A Prospective Multicenter Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate whether the IOTA ADNEX model and the Two‐Step Strategy improve triage and referral of adnexal masses in routine gynaecologic care compared with the RMI and to identify an appropriate malignancy‐risk threshold. Design Prospective multicenter cohort study. Setting Thirteen non‐tertiary hospitals and clinics and one tertiary
Nikoline Schou Karlsen, Eva Dreisler, Claus Kim Høgdall, Estrid Solyom Høgdall, Mona Aarenstrup Karlsen, Thomas Alexander Gerds, Guðbjörg Andrésdóttir, Lea Langhoff‐Thuesen, Malene Merete Forstholm, Abelone Elisabeth Sakse   +9 more
wiley   +1 more source