Results 161 to 170 of about 174,530 (347)

A Critical Review of the 2025 RSHE Guidance and Alternative Approach Framed in Safe Uncertainty

open access: yesChildren &Society, EarlyView.
ABSTRACT This policy review critically examines the English government's 2025 statutory guidance on Relationships Education, Relationship and Sex Education and Health Education (RSHE), analysing its educational assumptions, strengths and limitations through the lens of safe uncertainty.
Emily Setty, Jonny Hunt
wiley   +2 more sources

The Place of Marginalization in Bioethics: Do We Need the Concept?

open access: yesBioethics, EarlyView.
ABSTRACT Marginalization is a widely studied phenomenon and recognized as a critical topic in relation to health, shaping health inequities, access to resources, health outcomes, and policy decisions. However, despite its normative importance for health and justice, its conceptual role in bioethics remains unclear.
Elisabeth Langmann, Verina Wild
wiley   +1 more source

Adnexal mass with extremely high levels of CA-125 and CA19-9 but normal Human Epididymis Protein 4 (HE4) and Risk of Ovarian Malignancy Algorithm (ROMA): Endometriosis or ovarian malignancy? A case report

open access: yesInternational Journal of Reproductive BioMedicine, 2018
Background: It has been shown that Carbohydrate antigen (CA) 125 and CA 19-9 tumor markers are useful for diagnosis and follow up of ovarian carcinoma. Case: In this case, we reported the high level of CA-125 and CA 19-9 with large right ovarian intact ...
Sepideh Khodaverdi   +1 more
doaj  

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

open access: yesBJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui   +2 more
wiley   +1 more source

ENDOMETRIOSIS

open access: yesClinical Obstetrics and Gynecology, 1952
openaire   +2 more sources

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

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