Results 101 to 110 of about 200,055 (385)
Advanced Science, EarlyView.This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang +8 more
wiley +1 more source
Middle East Fertility Society Journal, 2015 Objective: To study the histopathology of endometrium and the serum concentration of sex steroid hormones in different types of atrophic endometrium associated with postmenopausal uterine bleeding (PMB). Design: Prospective observational study.
Dina Gamal Eldeen Elkholi +1 more
doaj +1 more source
Does dysbiotic endometrium affect blastocyst implantation in IVF patients?
Journal of Assisted Reproduction and Genetics, 2019 To analyze the pregnancy outcomes of IVF patients presenting eubiotic or dysbiotic endometrium at the time of embryo transfer and to analyze what bacterial profiles are suitable for embryo implantation.
T. Hashimoto, K. Kyono
semanticscholar +1 more source
Advanced Science, EarlyView.ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma +18 more
wiley +1 more source
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
, 2020 Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna +8 more
core +1 more source
Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity [PDF]
, 2015 The dysregulation of endometrial immune response to bacterial lipopolysaccharide (LPS) has been implicated in uterine disease and infertility in the postpartum dairy cow, although the mechanisms are not clear.
Abudureyimu, A +4 more
core +1 more source
JBRA Assisted Reproduction, 2018 Objective To improve endometrial quality and implantation rates after the administration of platelet-rich plasma in patients with refractory endometrium.
A. Molina +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang +8 more
wiley +1 more source
Comparison of T and NK lymphocyte subsets between human endometrial tissue and peripheral blood
Central European Journal of Immunology, 2019 Immune profiles in endometrium may be changed in patients with IVF failure and its possible correlations with immune parameters in peripheral blood are important for the diagnostic approach.
Viktor Chernyshov +3 more
doaj +1 more source
Global gene expression in endometrium of high and low fertility heifers during the mid-luteal phase of the estrous cycle [PDF]
, 2014 peer-reviewedBackground In both beef and dairy cattle, the majority of early embryo loss occurs within the first 14 days following insemination.
Diskin, Michael G. +5 more
core +1 more source