Results 191 to 200 of about 94,099 (313)
Limited pelvic radiotherapy in post-operative uterine carcinoma. [PDF]
Alexander HN +4 more
europepmc +1 more source
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho +8 more
wiley +1 more source
Single cell multiomics revealed fibrotic trajectories of endometrial cells and interaction with the pro-fibrotic macrophages in intrauterine adhesion. [PDF]
Li Y +18 more
europepmc +1 more source
Abstract Objective Heavy menstrual bleeding is one of the most common gynecologic disorders among women of reproductive age and has a significant impact on their physical, psychological, and social well‐being. Although international guidelines recommend medical therapy as the first‐line treatment, it may prove ineffective, poorly tolerated, or ...
Jonas Rudaitis +3 more
wiley +1 more source
Endometrial organoid and stromal cultures demonstrate donor-derived cellular origin of the endometrium after uterus transplantation. [PDF]
Meisl LM +7 more
europepmc +1 more source
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul +3 more
wiley +1 more source
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni +26 more
wiley +1 more source
Endometrioid Intraepithelial Neoplasia in the Secretory Phase: Morphologic and Biomarker Diagnostic Features in a Common, Overlooked Setting. [PDF]
Means AM +11 more
europepmc +1 more source
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang +18 more
wiley +1 more source
The interaction between inflammation and estrogen in adenomyosis : from molecular mechanisms to therapeutic strategies. [PDF]
Li F +6 more
europepmc +1 more source

