Results 231 to 240 of about 159,563 (339)

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

The mechanism study of targeting DPP4 in regulating ferroptosis and its influence on endometrial receptivity in PCOS. [PDF]

Biol Sex Differ
Zhang J, Wang R, Tian X, Ding N, He Y, Wang K, Tao C, Cai J, Jian Q, Wang F.   +9 more
europepmc   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stromal cells. [PDF]

Front Pharmacol
Lai H, Jia J, Kuang Z, Lu J, Zeng Y.
europepmc   +1 more source

Endometrium [PDF]

, 2020
openaire   +1 more source

Preliminary Study on the Value of Contrast‐Enhanced Ultrasound in Enhancing Early Vascular Architecture for the Differential Diagnosis of Benign and Malignant Endometrial Lesions

Journal of Clinical Ultrasound, EarlyView.
This study aimed to analyze the microvascular morphology and distribution (i.e., early vascular architecture) of endometrial carcinoma lesions during the early enhancement phase using contrast‐enhanced ultrasound (CEUS). The results confirmed that quantitative parameters based on the early vascular architecture possess certain diagnostic efficacy for ...
Qiuyun Huang, Yunhao Luo, Jia Xu, Danlin Wen, Fangqin Liu, Jing Miao, Lang Qiao   +6 more
wiley   +1 more source

Identification of novel differentiation trajectories and gene network associations with ectopic pregnancy in fallopian tube epithelium. [PDF]

Hum Reprod
Wright LI, Wangsaputra I, Garner T, Sharps MC, Sturmey R, Ruane PT, Stevens A.   +6 more
europepmc   +1 more source

The Application Value of Transvaginal Three‐Dimensional Ultrasonography in the Diagnosis of Adenomyosis of the Uterus

Journal of Clinical Ultrasound, EarlyView.
In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li, Zhen Zong, Xiaoman Wang, Hebin Zhang   +3 more
wiley   +1 more source

Sustained STING-IRF7 signaling aggravates LPS-induced endometrial inflammation via excessive neutrophil extracellular traps generation. [PDF]

Front Immunol
Chu M, Ma D, Song Z, Liang L, Xing F, Bao H.   +5 more
europepmc   +1 more source