Results 281 to 290 of about 143,576 (351)

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Molecular Impact of Metabolic and Endocrine Disturbance on Endometrial Function in Polycystic Ovary Syndrome. [PDF]

Int J Mol Sci
Parker J, O'Brien C, Uppal T, Tremellen K.   +3 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Macrophages in endometriosis: key roles and emerging therapeutic opportunities-a narrative review. [PDF]

Reprod Biol Endocrinol
Wang X, Wu N, Xue Q.
europepmc   +1 more source

Role of Gynecologic Findings in Interstitial Cystitis/Bladder Pain Syndrome: A Consensus

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To evaluate the role of gynecologic findings in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by reviewing current international guidelines and identifying relevant gynecologic co‐morbidities. Methods This consensus statement was developed through a systematic four‐phase process: (1) comprehensive literature review across ...
Marie E. Sullivan, Amr El Haraki, Anna Padoa, Katy Vincent, Kristene E. Whitmore, Mauro Cervigni   +5 more
wiley   +1 more source

Targeting steroid receptor coactivators for the treatment of benign female reproductive disorders. [PDF]

Endocr Connect
Park Y, Jeong J, Kim E, Sung N, Han SJ.
europepmc   +1 more source

A spatial transcriptomics dataset of the endometrium from repeated implantation failure patients. [PDF]

Sci Data
Zhang Y, Pan J, Liu Z, Zheng M, Liu R, Lei L, Liu H, Wang P.   +7 more
europepmc   +1 more source

Impact of Tamoxifen on Endometrial Thickness in Women With Thin Endometrium Following Estrogen Therapy During Frozen-Thawed Embryo Transfer. [PDF]

Clin Case Rep
Zaree M, Namavar Jahromi B, Parsanezhad ME, Mosallanezhad Z, Hashemi SS, YaghoobiGorgi F, Salehi A.   +6 more
europepmc   +1 more source

Diagnosis and classification of uterine fibroids. [PDF]

Int J Gynaecol Obstet
Lakabi R, Harth S, Meinhold-Heerlein I, Olsthoorn AV, Munro MG, Murji A.   +5 more
europepmc   +1 more source

Endothelin Receptors in Human Myometrium and Endometrium

, 1996
Railortega Chavez
openalex   +1 more source