Results 61 to 70 of about 17,429 (235)

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, Volume 6, Issue 12, December 2025.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

Current Understanding of the Pathophysiology of Myocardial Fibrosis and Its Quantitative Assessment in Heart Failure

Frontiers in Physiology, 2017
Myocardial fibrosis is an important part of cardiac remodeling that leads to heart failure and death. Myocardial fibrosis results from increased myofibroblast activity and excessive extracellular matrix deposition.
Tong Liu, Deli Song, Jianzeng Dong, Pinghui Zhu, Jie Liu, Jie Liu, Wei Liu, Xiaohai Ma, Lei Zhao, Shukuan Ling   +9 more
doaj   +1 more source

Inflammation and genetics in myo‐pericardial diseases: Insights from the Italian Study Group on Cardiomyopathies and Pericardial Diseases

ESC Heart Failure, Volume 12, Issue 6, Page 3987-3999, December 2025.
Proposed management of myo‐pericardial diseases. A systematic interdisciplinary approach to myo‐pericardial disease is essential to reach a correct diagnosis, starting from multiparametric characterization including EKG, echocardiography with GLS, laboratory exams and CMR or, in case of electric or haemodynamic instability, EMB.
Marco Merlo, Giulia Bassetto, Antonio Cannatà, Alberto Aimo, Camillo Autore, Barbara Bauce, Elena Biagini, Francesco Cappelli, Silvia Castelletti, Flavio D'Ascenzi, Cesare de Gregorio, Giuseppe Limongelli, Francesca Marzo, Beatrice Musumeci, Giacomo Tini, Roberto Pedrinelli, Pasquale Perrone Filardi, Gianfranco Sinagra, Massimo Imazio   +18 more
wiley   +1 more source

When Hypereosinophilia Leads to Stroke [PDF]

, 2017
AFIP1L1-PDGFRA fusion can only be confirmed through molecular and cytogenetic investigations causing a delay in the diagnosis. However, patients with this mutation need urgent treatment because they present hypereosinophilia which may be associated with ...
Chalayer, Emilie, Pelissier, Aude, Tardy, Bernard   +2 more
core   +3 more sources

Right Ventricular Endomyocardial Fibrosis Presenting With Ventricular Tachycardia And Apical Thrombus - An Interesting Presentation

Indian Pacing and Electrophysiology Journal, 2009
Endomyocardial fibrosis is a progressive disease of unknown origin affecting children and young adults. It involves inflow portion of right and/or left ventricle and apex. It may be associated with thrombus.
Amitesh Aggarwal, Bineet Sinha, Surender Rajpal, Shridhar Dwivedi, Vishal Sharma   +4 more
doaj  

Computational modelling of myocardial metabolism in patients with advanced heart failure

European Journal of Heart Failure, Volume 27, Issue 12, Page 3411-3422, December 2025.
Study design and key findings. Proteomics‐informed, patient‐specific computational models of myocardial metabolism reveal reduced ATP production capacity and a lower fatty acid‐to‐glucose utilisation ratio in heart failure, which correlated with functional recovery following mechanical unloading.
Niklas Beyhoff, Vera M. Braun, Marieluise Kirchner, Lucy E.M. Finnigan, Christoph Knosalla, István Baczkó, Evgenij Potapov, Ulrich Kintscher, Tilman Grune, Titus Kuehne, Hermann‐Georg Holzhütter, Philipp Mertins, Damian J. Tyler, Hendrik Milting, Betty Raman, Oliver J. Rider, Stefan Neubauer, Nikolaus Berndt   +17 more
wiley   +1 more source

Presence of circulating anti-myosin antibodies in endomyocardial fibrosis. [PDF]

PLoS Neglected Tropical Diseases, 2010
BackgroundEndomyocardial Fibrosis (EMF) is a tropical restrictive cardiomyopathy of unknown etiology with high prevalence in Sub-Saharan Africa, for which it is unclear whether the primary target of injury is the endocardial endothelium, the ...
Ana Olga Mocumbi, Najma Latif, Magdi H Yacoub   +2 more
doaj   +1 more source

Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage [PDF]

, 2020
Glycogenin is considered to be an essential primer for glycogen biosynthesis. Nevertheless, patients with glycogenin-1 deficiency due to biallelic GYG1 (NM_004130.3) mutations can store glycogen in muscle.
Dellgren, Göran, Glamuzina, Emma, Hedberg-Oldfors, Carola, Hernandez-Lain, Aurelio, Kornblum, Cornelia, Oldfors, Anders, Roach, Peter, Sandstedt, Joakim, Tasca, Giorgio, Thomsen, Christer, Visuttijai, Kittichate   +10 more
core   +1 more source

Clustering in dilated cardiomyopathy at initial evaluation: An effective tool for clinical stratification

European Journal of Heart Failure, Volume 27, Issue 12, Page 3040-3047, December 2025.
Visual description of study design and main results. BBB, bundle branch block; ECG, electrocardiogram; MVA, major ventricular arrhythmia; SCD, sudden cardiac death. Abstract Aims Dilated cardiomyopathy (DCM) has a highly variable presentation and disease course. Current stratification strategies are complex and require multimodality evaluation.
Ilaria Gandin, Maria Perotto, Alessia Paldino, Giovanni Baj, Denise Zaffalon, Andrea Pezzato, Cinzia Crescenzi, Fabiana Romeo, Annamaria Martino, Francesca Fanisio, Federica Toto, Maddalena Rossi, Marta Gigli, Matteo Dal Ferro, Leonardo Calò, Gianfranco Sinagra, Marco Merlo   +16 more
wiley   +1 more source

Does quantitative left ventricular regional wall motion change after fibrous tissue resection in endomyocardial fibrosis?

Clinics, 2009
OBJECTIVES: We compared left ventricular regional wall motion, the global left ventricular ejection fraction, and the New York Heart Association functional class pre- and postoperatively.
Vera Maria Cury Salemi, Fabio Fernandes, Raquel Sirvente, Luciano Nastari, Leonardo Vieira Rosa, Cristiano A. Ferreira, José Luiz Barros Pena, Michael H. Picard, Charles Mady   +8 more
doaj   +1 more source