Results 271 to 280 of about 24,423 (298)

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

Nature, 2012
PIWI-interacting RNAs (piRNAs) silence transposons to maintain genome integrity in animal germ lines. piRNAs are classified as primary and secondary piRNAs, depending on their biogenesis machinery. Primary piRNAs are processed from long non-coding RNA precursors transcribed from piRNA clusters in the genome through the primary processing pathway ...
Hiroshi Nishimasu, Kuniaki Saito, Luc Bonnefond   +2 more
exaly   +4 more sources

Influenza Virus Endoribonuclease

2001
The influenza virus polymerase complex contains two associated enzymatic activities, an endoribonuclease and a RNA-dependent RNA polymerase activity. Both activities have so far been observed only with the complete polymerase complex consisting of three subunits, PB1, PB2, and PA.
Lisa Hooker, Klaus Klumpp, Balraj Krishan Handa   +2 more
openaire   +2 more sources

Chloroplast p54 Endoribonuclease

2001
Publisher Summary Much of the regulation of chloroplast gene expression has been assigned to stability determinants at the level of RNA precursors, including interactions of sequence and/or structural elements with their cognate binding proteins. A number of these proteins are known to assemble at the 5′-untranslated region (UTR) of chloroplast mRNAs,
Karsten Liere, Jörg Nickelsen, Gerhard Link   +2 more
openaire   +3 more sources

Overview of theLeishmaniavirusendoribonuclease and functions of other endoribonucleases affecting viral gene expression

The Journal of Experimental Zoology, 1998
Leishmaniaviruses (LRV) are double-stranded RNA viruses that persistently infect some strains of the protozoan parasite Leishmania. The identification of a short viral RNA transcript led to our discovery of an endoribonuclease activity of the LRV capsid protein.
Jean L. Patterson, Kyle J. Macbeth
openaire   +3 more sources

The role of endoribonucleases in the regulation of RNase R

Biochemical and Biophysical Research Communications, 2006
RNase R is an important exoribonuclease involved in the maturation and degradation of RNA. RNase R is co-transcribed with other genes in the same operon. In this report, we show that under physiological conditions maturation of these co-transcripts and the levels of RNase R are mainly dependent on the endoribonuclease RNase E.
Cecília M. Arraiano, Fátima Cairrão
openaire   +3 more sources

Purification and characterization of a novel mammalian endoribonuclease

Journal of Cellular Biochemistry, 2005
AbstractEndonuclease‐mediated mRNA decay appears to be a common mode of mRNA degradation in mammalian cells, but yet only a few mRNA endonucleases have been described. Here, we report the existence of a second mammalian endonuclease that is capable of cleaving c‐myc mRNA within the coding region in vitro.
Joel C. Urquhart, Kirk Bergstrom, Alaeddin Tafech, Erin Doyle, Chow H. Lee   +4 more
openaire   +3 more sources

A microsomal endoribonuclease from rat liver

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1980
An endoribonuclease has been purified about 320-fold from the microsomes of rat liver. The enzyme had an apparent molecular weight of 54 000-58 000 and produced oligonucleotides, each consisting of 3-7 nucleotides from poly(A) and poly(U). No mononucleotide was obtained by the enzymatic hydrolysis of poly(A) and poly(U) under standard coditions.
Seiyu Hirose, Kazuei Igarashi, Takemi Takayama, Kaori Watanabe, Hiroshi Kumagai, Kazue Sugimoto   +5 more
openaire   +2 more sources

Endoribonuclease activities of Trypanosoma brucei mitochondria

Molecular and Biochemical Parasitology, 2002
RNA editing in kinetoplastids is a type of post-transcriptional processing that changes mitochondrial mRNA sequences by the addition or deletion of uridines. Multiple enzymatic activities, such as endoribonuclease and RNA ligase, are associated with this process and exist in a multienzyme complex.
Barbara A. Morach, Setareh S. Palazzo, Reza Salavati, Robert P. Igo, Aswini K. Panigrahi, Kenneth Stuart   +5 more
openaire   +3 more sources

Bacteriophage T4 RegB Endoribonuclease

2001
Publisher Summary The development of bacteriophage T4 is largely determined by a precisely coordinated subversion of the host RNA polymerase to permit initiation from different classes of T4-specific promoters. The synthesis, in cascade, of regulatory elements that modify the transcription apparatus, ensures the temporal ordering of the developmental
openaire   +2 more sources

Nucleotide binding architecture for secreted cytotoxic endoribonucleases

Biochimie, 2013
Vertebrate secreted RNases are small cationic protein endowed with an endoribonuclease activity that belong to the RNase A superfamily and display diverse cytotoxic activities. In an effort to unravel their mechanism of action, we have analysed their nucleotide binding recognition patterns. General shared features with other nucleotide binding proteins
Mohammed Moussaoui, M. Victòria Nogués, Jose A. Blanco, Ester Boix   +3 more
openaire   +3 more sources