Results 41 to 50 of about 2,485 (124)

Gut microbiota as a novel therapeutic target for eating disorders and obesity

open access: yesBritish Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė   +5 more
wiley   +1 more source

Endorphins as the Mediator of Learned Helplessness

open access: yes, 1982
This study evaluates endorphins as a mediator of learned helplessness. Thirty-two male rats (i.e. Evans hooded) were randomly assigned to one of four groups: an escape group, a helpless group, a helpless group treated with naloxone, and a helpless group ...
Meier, Patrick R.   +2 more
core   +1 more source

Evaluation of the effects of dexmedetomidine and midazolam on plasma and cerebrospinal fluid beta-endorphin levels in rats

open access: yesMedicine Science, 2021
Endorphins are endogenous peptides that play a role in the regulation of pain, behavior, neuroendocrine and autonomic functions. In our study, we aimed to investigate the role of β endorphins in these effects of midazolam and dexmedetomidine.
Canan Kucuk, Nihal Kadiogullari
doaj   +1 more source

GLP‐1 receptor activation attenuates chronic migraine‐like behaviour: Sex‐specific modulation of opioid‐ and endocannabinoid‐related pathways

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Chronic migraine (CM) is a highly disabling condition that remains suboptimally treated. Metabolic disturbances may trigger migraine chronification, whereas impaired endogenous pain inhibition contributes to CM development. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), used for type 2 diabetes and obesity, show efficacy ...
Katarina Sićović   +6 more
wiley   +1 more source

Pain pathways and mechanisms of neuropathic pain

open access: yesActa Neurológica Colombiana, 2007
Several neural steps are involved in the processing of noxious signals that can lead to the experience of pain. Nociceptors readily respond to different noxious modalities such as thermal, mechanical or chemical stimuli, but nociceptors do not respond ...
Oscar A. de Leon-Casasola
doaj   +2 more sources

The effect of endomorphins-1, -2 on the production of reactive oxygen species and the absorption activity of innate immunity cells in vitro and in vivo

open access: yesActa Biomedica Scientifica, 2022
Background. A high percentage of people in the world suffer from acute or chronic pain, the treatment of which is based on the introduction of morphine and its derivatives, agonists of the µ-opioid receptors, leading to the development of addiction in ...
Ya. A. Kadochnikova, S. V. Gein
doaj   +1 more source

Beyond Bouncing Back: Exploring Undergraduate Dental Professional Students' Perceptions of Resilience

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The first signs of mental health issues in dentistry manifest as early as undergraduate training, thus it is essential to delve into the concept of resilience to equip those studying and working in dentistry with the resources to cultivate a positive mindset.
Vaida Kaunaite, Marina Harris
wiley   +1 more source

Auricular Acupressure Effectively Reduces Labor Anxiety in Primigravidae by Increasing β-Endorphin Levels

open access: yesFolia Medica Indonesiana, 2023
Highlights: 1. Auricular acupressure at the Shenmen point is effective in reducing anxiety. 2. Auricular acupressure is more practical than body acupressure since it does not interfere with expectant mothers' mobilization. 3.
Setiawandari   +3 more
doaj   +1 more source

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

open access: yesInternational Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta   +4 more
wiley   +1 more source

INFLUENCE OF ENDORPHINS ON THE MIGRATION OF MOLLUSCAN HEMOCYTES

open access: yes, 1994
The influence of endorphins on the hemocyte migration of two molluscs, Planorbarius corneus and Viviparus ater, was tested. The whole sequence of beta-endorphin and its N- and C-terminal fragments stimulate hemocyte migration.
BERNARDI M   +9 more
core   +1 more source

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