Results 121 to 130 of about 565,881 (286)

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Success of Systemic Methotrexate Administration Versus Laparoscopic Salpingostomy in Ectopic Pregnancy

Gynecology Obstetrics & Reproductive Medicine, 2011
OBJECTIVE: In this study, we tried to compare the efficacies of laparoscopic salpingostomy and medication with a single dose of Methotrexate (50mg/m2) in ectopic pregnancy to determine the differences between the two methods in terms of treatment ...
Özlem Gün Eryılmaz, Özlem Moraloğlu, Kerem Doğa Seçkin, Mahmut İlkin Yeral, Ayhan Sucak, Hacer Cavidan Gülerman   +5 more
doaj  

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

AI‐Enhanced Vibrational Capsule for Minimally Invasive Detection of Abnormal Bowel Tissue

Advanced Science, EarlyView.
A fully integrated vibration‐assisted capsule is presented for the minimally invasive detection of bowel lesions. The capsule incorporates a wireless sensor and an eccentric motor to probe tissue mechanics in situ. By coupling triaxial vibration signals with AI‐based classification and analytical modeling, the system enables early, non‐visual ...
Xizheng Fang, Yao Yan, Kenneth Omokhagbo Afebu, Andrew Bickerdike, Bo Tian, Yang Liu, Shyam Prasad   +6 more
wiley   +1 more source

Artificial intelligence-assisted endobronchial ultrasound for differentiating between benign and malignant thoracic lymph nodes: a meta-analysis

BMC Pulmonary Medicine
Background Endobronchial ultrasound (EBUS) is a widely used imaging modality for evaluating thoracic lymph nodes (LNs), particularly in the staging of lung cancer.
Fei Tang, Xian-Kui Zha, Wei Ye, Yue-Ming Wang, Ying-Feng Wu, Li-Na Wang, Li-Ping Lyu, Xiao-Mei Lyu   +7 more
doaj   +1 more source

A Strain Decoupling Packaging Strategy for High‐Fidelity Ultrathin Silicon Shape Sensors for Soft Medical Robotics

Advanced Science, EarlyView.
Reliable soft sensors are essential for precise control in soft medical robots such as endoscopes. We developed ultrathin silicon piezoresistive sensors and their oil‐lubricated slidable packaging, which enables high‐fidelity shape sensing of silicon gauges by mechanically isolating the sensing element within a dual‐layer film.
Hao Liu, Masahito Takakuwa, Michitaka Yamamoto, Yiwen Wang, Tomoyuki Yokota, Takao Someya, Toshihiro Itoh, Seiichi Takamatsu   +7 more
wiley   +1 more source

The association of preoperative hematologic parameters with short‐term clinical outcomes in rectal cancer: A feature importance analysis

Cancer Medicine
Background Various hematologic parameters have been proposed as prognostic factors in rectal cancer management, but data are conflicting and unclear.
Ala Orafaie, Fatemeh Shahabi, Ali Mehri, Majid Ansari, Sajjad Kasraeifar, Mahdie Ghiyasi, Maryam Saberi‐Karimian, Abbas Abdollahi, Seyyed Mohammad Tabatabaei   +8 more
doaj   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Dendritic Nano‐Based Slippery Coating by Synergistic Mechanical and Electrostatic Interactions with Persistent and Exceptional Combats Thrombosis

Advanced Science, EarlyView.
A novel dendritic nano‐based slippery coating (DNSC), fabricated by encapsulating carboxyl silicone oil within amino dendritic silica nanoparticles and co‐embedding them in an epoxy resin matrix. The dendritic architecture enhances nanoparticle dispersion in the matrix and establishes mechanical interlock.
Shu Zhang, Yao Shen, Juan Liu, Qing Zeng, Yunze Ma, Shuping Chen, Taiyu Nan, Xiaoying Qiu, Jiayi Yu, Tao Fan, Guozhi Huang, Jihua Zou, Chengduan Yang   +12 more
wiley   +1 more source

Acute Myeloid Leukemia Presenting as Obstructive Jaundice Caused by Granulocytic Sarcoma

Gut and Liver, 2007
We report a rare case of granulocytic sarcoma infiltrating the bile duct in a patient with acute myeloid leukemia. A 23-year-old man presented with jaundice and weight loss. A peripheral blood smear revealed blast cells, and the results of an examination
doaj   +1 more source