Vocal Outcomes After Cell‐Based Outer Vocal Fold Implant in Porcine Bilateral Vocal Fold Resection
Cell‐based outer vocal fold replacement (COVR) was evaluated in a porcine model of bilateral vocal fold injury using longitudinal acoustic analysis and histologic assessment. COVR implantation resulted in recovery of the nonperiodic acoustic parameter Q50 to preoperative levels by 6 months, with implanted human adipose‐derived stem cells detected in 7 ...
Keer Zhang +7 more
wiley +1 more source
Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz +7 more
wiley +1 more source
The Subhyoid Approach for Base of Tongue Tumors: Description of A Novel Surgical Technique
The sub‐hyoid approach is a novel open surgical technique for selected deeply infiltrative base of tongue tumors, providing direct access and allowing full‐thickness resection while preserving the tongue neurovascular structures. Thyro‐hyoido‐pexy restores hyo‐laryngeal suspension without flap reconstruction, with the aim of preserving swallowing ...
Livio Presutti +6 more
wiley +1 more source
Global Multidisciplinary Variation in Idiopathic Subglottic Stenosis Surgical Management
This international cross‐sectional survey of 193 clinicians across 42 countries reveals substantial global and multidisciplinary variation in the surgical management of idiopathic subglottic stenosis (iSGS). While endoscopic dilation remains near‐universally utilized, practice patterns differ significantly regarding technical execution, adjuvant ...
Emilie A. C. Dronkers +7 more
wiley +1 more source
Underwater endoscopic mucosal resection for superficial nonampullary duodenal adenomas
Background and study aim Underwater endoscopic mucosal resection (UEMR) was recently developed in a Western country. A prospective cohort study to investigate the effectiveness of UEMR was conducted in patients with small superficial nonampullary ...
Tomofumi Akasaka +17 more
core +1 more source
Association of Neighborhood Deprivation With Breslow Thickness in Head and Neck Cutaneous Melanoma
Neighborhood socioeconomic deprivation, measured by the Area Deprivation Index (ADI), was independently associated with greater Breslow thickness in patients with primary head and neck cutaneous melanoma treated at a single tertiary care center. Patients residing in the most deprived neighborhoods had, on average, 1.40 mm greater tumor thickness ...
Evan A. Thomas +7 more
wiley +1 more source
Occupational HPV Exposure in Otolaryngology: A Scoping Review of Detection, Risk, and Prevention
This scoping review identified 10 studies evaluating occupational HPV exposure in otolaryngology. HPV DNA was detected in surgical plume following some HPV‐related procedures, including up to 56.7% of CO2 laser plume samples, while the only study assessing oral HPV among exposed clinicians reported a prevalence of 2.2%, not exceeding that of the ...
Ying Jie Li +2 more
wiley +1 more source
Therapeutic JAK Inhibition in Idiopathic Subglottic Stenosis
Three patients with idiopathic subglottic stenosis and rheumatoid arthritis began JAK inhibitor therapy, after which the mean surgical‐free interval between endoscopic dilations rose from 317 to 631 days and the annualized dilation rate fell from 1.24 to 0.38 per patient‐year. Figure 2 shows this as a per‐patient timeline.
Riley M. Larkin +5 more
wiley +1 more source
How I Do It: Nasoseptal Flap for Reconstruction of Isolated Soft Palate Defect
A vascularized nasoseptal flap (NSF) provides a novel transnasal option for repairing soft palatal fistulas when traditional transoral flaps have failed or are unavailable, potentially avoiding the morbidity of regional or free tissue transfer. In the current patient who had an 8 × 6 mm soft palatal fistula, the NSF was harvested from the septum and ...
Vincent M. Desiato +3 more
wiley +1 more source
Invention of the Flexible Fiberoptic Nasopharyngolaryngoscope: Perspectives From the East
The fiberoptic nasopharyngolaryngoscope was developed in 1967 by Drs. Masayuki Sawashima, Hajime Hirose, and Osamu Fujimura at the University of Tokyo's Research Institute of Logopedics and Phoniatrics (RILP), building on Dr. Shigeto Ikeda's 1962 fiberoptic bronchoscope during Japan's postwar surge in technological innovation.
Carolyn J. Khoury +7 more
wiley +1 more source

