Direct endoscopic necrosectomy in infected pancreatic necrosis using lumen-apposing metal stents: Early intervention does not compromise outcome [PDF]
Background and study aims Infection of pancreatic necrosis is a dreaded complication requiring an intervention. Nevertheless, the optimal timing of the first intervention is unclear, and consensus data are sparse.
David Albers +4 more
doaj +2 more sources
Postponed endoscopic necrosectomy results in a lower rate of additional intervention for infected walled-off necrosis [PDF]
Although endoscopic necrosectomy (EN) is more frequently used to manage walled-off necrosis (WON), there is still debate over how much time should pass between the initial stent placement and the first necrosectomy.
Songting Wu +6 more
doaj +2 more sources
Standardized approach to removal of lumen apposing metal stents following endoscopic necrosectomy: one size does not fit all [PDF]
Background: Walled-off necrosis (WON) is a sequela of acute necrotizing pancreatitis preferentially managed with lumen apposing metal stents (LAMS). Adverse events including buried stent syndrome and bleeding have been associated with a longer duration ...
Robert Dorrell +4 more
doaj +2 more sources
Open Surgical versus Minimal Invasive Necrosectomy of the Pancreas-A Retrospective Multicenter Analysis of the German Pancreatitis Study Group. [PDF]
Necrotising pancreatitis, and particularly infected necrosis, are still associated with high morbidity and mortality. Since 2011, a step-up approach with lower morbidity rates compared to initial open necrosectomy has been established. However, mortality
Sebastian Rasch +27 more
doaj +4 more sources
Endoscopic Versus Surgical Management for Infected Necrotizing Pancreatitis and Walled-Off Necrosis: A Systematic Review of Randomized Controlled Trials [PDF]
Background and Objectives: Infected necrotizing pancreatitis and walled-off necrosis are associated with substantial morbidity and mortality. The evolution from open necrosectomy to minimally invasive and endoscopic strategies has improved outcomes, yet ...
Manuela Mastronardi +8 more
doaj +2 more sources
Is endoscopic necrosectomy the way to go?
Pancreatic necrosis with the formation of walled-off collections is a known complication of severe acute pancreatitis. Infected necrotic pancreatic collections are associated with a high mortality rate.
James Weiquan Li, Tiing Leong Ang
doaj +3 more sources
Endoscopic Step‐up Approach for Walled‐off Necrosis After Acute Pancreatitis
This review outlines current interventional strategies for treating symptomatic walled‐off necrosis (WON) after necrotizing pancreatitis. Mortality from acute pancreatitis has improved, but late mortality, particularly from infected necrosis, remains a ...
Shuntaro Mukai +13 more
doaj +2 more sources
Surgery for necrotizing acute pancreatitis: surgical approach, morbidity and challenges encountered: experience from a tertiary care hepatopancreatobiliary unit in Sri Lanka [PDF]
BackgroundInfected pancreatic necrosis (IPN) remains a life-threatening complication of acute pancreatitis. While minimally invasive “step-up” strategies are now standard, their implementation in resource-limited settings is often constrained by ...
Duminda Subasinghe +4 more
doaj +2 more sources
Endoscopic ultrasonography (EUS)–guided drainage followed by direct endoscopic necrosectomy (DEN) is widely used as a minimally invasive treatment for walled-off necrosis (WON).
Yasuo Otsuka +7 more
doaj +2 more sources
Hydrogen Peroxide Flushes for Necrotizing Pancreatitis in a High-Risk Surgical Patient: A Pathway for Durable Response Without Additional Endoscopic Intervention [PDF]
Necrotizing pancreatitis (NP) is characterized by severe pancreatic inflammation with necrosis and a systemic inflammatory response. We describe the case of a 32-year-old female with NP successfully treated with a modified protocol using hydrogen ...
Smriti Kochhar +2 more
doaj +2 more sources

