Results 101 to 110 of about 1,065,392 (387)

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Risk Factors and Clinical Outcomes of 54 Cases of Rectal Neuroendocrine Tumors with Incomplete Resection: A Retrospective Single-Center Study

Therapeutics and Clinical Risk Management, 2021
Yan Li,* Fei Pan,* Gang Sun, Zi-kai Wang, Ke Meng, Li-hua Peng, Zhong-sheng Lu, Yan Dou, Bin Yan, Qing-sen Liu Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, People’s Republic of China*These authors ...
Li Y, Pan F, Sun G, Wang ZK, Meng K, Peng LH, Lu ZS, Dou Y, Yan B, Liu QS   +9 more
doaj  

Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry. [PDF]

, 2019
Volumetric laser endomicroscopy (VLE) uses optical coherence tomography (OCT) for real-time, microscopic cross-sectional imaging. A US-based multi-center registry was constructed to prospectively collect data on patients undergoing upper endoscopy during
Berzin, T, Cash, B, Chang, K, DeMeester, S, Di Palma, JA, Diehl, D, Ganguly, E, Gonda, T, Gordon, S, Gress, F, Hagen, J, Hasan, M, Hawes, R, Hyder, S, Jobe, B, Joshi, V, Kahaleh, M, Kedia, P, Khara, H, Komatsu, Y, Konda, V, Lee, C, Lipham, J, Malik, Z, Mashimo, H, McKinley, M, Navaneethan, U, Oh, D, Pleskow, D, Poneros, J, Rodriguez, R, Rothstein, R, Samarasena, J, Sawhney, M, Schnoll-Sussman, F, Sejpal, DV, Sethi, A, Sharaiha, R, Sharzehi, K, Siddiqui, UD, Singh, S, Smith, MS, Tarnasky, P, Thakkar, S, Trindade, AJ, Wallace, M, Waxman, I, Wolfsen, H   +47 more
core  

Laparoscopic resection of gastric GISTs. Where do we stand now? A single-centered experience [PDF]

, 2019
Introduction. Gastrointestinal stromal tumors (GISTs) represent a rare type of gastrointestinal neoplasms. Resection with negative margins has been established as a mainstay treatment, but laparoscopic resections are still open to debate.
Alecu, Lucian, Nitipir, Cornelia, Slavu, Iulian, Stanculeanu, Dana L, Tulin, Adrian   +4 more
core   +2 more sources

Clinical impact of Endoscopic Surgical Skill Qualification System (ESSQS) by Japan Society for Endoscopic Surgery (JSES) for laparoscopic distal gastrectomy and low anterior resection based on the National Clinical Database (NCD) registry

Annals of Gastroenterological Surgery, 2020
This study aimed to evaluate the association between surgeons certified via the Endoscopic Surgical Skill Qualification System (ESSQS) of the Japan Society for Endoscopic Surgery (JSES) and surgical outcomes of laparoscopic distal gastrectomy (LDG) and ...
T. Akagi, H. Endo, M. Inomata, H. Yamamoto, Toshiyuki Mori, K. Kojima, H. Kuroyanagi, Y. Sakai, K. Nakajima, H. Shiroshita, T. Etoh, Y. Saida, Seiichiro Yamamoto, H. Hasegawa, H. Ueno, Y. Kakeji, H. Miyata, Y. Kitagawa, M. Watanabe   +18 more
semanticscholar   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Association of Poor Differentiation or Positive Vertical Margin with Residual Disease in Patients with Subsequent Colectomy after Complete Macroscopic Endoscopic Resection of Early Colorectal Cancer

Gastroenterology Research and Practice, 2017
In the presence of unfavorable pathologic results after endoscopic resection of colorectal cancer, colectomy is routinely performed. We determined the risk factors for residual diseases in patients with colectomy after complete macroscopic endoscopic ...
Ki Ju Kim, Hyun Seok Lee, Seong Woo Jeon, Sun Jin, Sang Won Lee   +4 more
doaj   +1 more source

Dissection-enabled scaffold-assisted resection (DeSCAR): a novel technique for resection of residual or non-lifting gastrointestinal neoplasia of the colon, expanded experience and follow-up

Endoscopy International Open, 2020
Background and study aims Colonic lesions may not be amenable to conventional endoscopic mucosal resection (EMR) due to previous manipulation, submucosal invasion, or lesion flatness.
Edward Villa, Matthew Stier, Kianoush Donboli, Christopher Grant Chapman, Uzma D. Siddiqui, Irving Waxman   +5 more
doaj   +1 more source

Combination of Ethoxybenzyl‐Diethylenetriamine Pentaacetic Acid‐Enhanced Magnetic Resonance Imaging and a Serum Biomarker Is Useful in the Diagnosis of Hepatic Sinusoidal Disorder After Chemotherapy Treatment

Annals of Gastroenterological Surgery, EarlyView.
ROC analyses of APRI score, EOB‐MRI, and a combination of EOB‐MRI and APRI score for blue liver. ABSTRACT Aim Sinusoidal obstruction syndrome (SOS), also known as “blue liver (BL),” is a common hepatic injury following oxaliplatin‐based chemotherapy in patients with colorectal liver metastases (CRLM).
Tomonari Shimagaki, Keishi Sugimachi, Takahiro Tomino, Takeshi Kurihara, Emi Onishi, Yutaro Shimomura, Kenji Shinozaki, Masaru Morita   +7 more
wiley   +1 more source