Results 111 to 120 of about 44,363 (283)

Availability, use, efficacy and safety of bevacizumab in European hereditary haemorrhagic telangiectasia centres

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction Bevacizumab, a vascular endothelial growth factor inhibitor, is used off‐label for treatment of severe anaemia related to epistaxis, gastrointestinal bleeding and/or severe hepatic arteriovenous malformations (HAVM) and right‐sided cardiac failure in patients with hereditary haemorrhagic telangiectasia (HHT).
Pernille D. Haahr   +18 more
wiley   +1 more source

Safety and efficacy of endoscopic submucosal dissection for rectal neoplasia: a multicenter North American experience. [PDF]

open access: yes, 2019
Background and aims  Rectal lesions traditionally represent the first lesions approached during endoscopic submucosal dissection (ESD) training in the West. We evaluated the safety and efficacy of rectal ESD in North America.
Aadam, Abdul Aziz   +31 more
core   +1 more source

Combined Biologics and Exclusive Enteral Nutrition Promote Early Transmural Healing and Improve Long‐Term Outcomes in Crohn's Disease: A Multicenter Retrospective Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Study design and flow chart. From October 2016 to 2024, we searched the Crohn’s disease (CD) patient databases of three IBD centers in Hubei Province and identified 598 CD patients. Among them, 179 were in clinical remission and 38 had mild disease and were therefore excluded based on the study criteria.
Haixia Ren   +16 more
wiley   +1 more source

Sedation for routine gastrointestinal endoscopic procedures: a review on efficacy, safety, efficiency, cost and satisfaction

open access: yesIntestinal Research, 2017
Most gastrointestinal endoscopic procedures are now performed with sedation. Moderate sedation using benzodiazepines and opioids continue to be widely used, but propofol sedation is becoming more popular because its unique pharmacokinetic properties make
Otto S. Lin
doaj   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik   +7 more
wiley   +1 more source

GastroNet: A robust attention‐based deep learning and cosine similarity feature selection framework for gastrointestinal disease classification from endoscopic images

open access: yesCAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Diseases of the Gastrointestinal (GI) tract significantly affect the quality of human life and have a high fatality rate. Accurate diagnosis of GI diseases plays a pivotal role in healthcare systems. However, processing large amounts of medical image data can be challenging for radiologists and other medical professionals, increasing the risk ...
Muhammad Nouman Noor   +5 more
wiley   +1 more source

Content-Based Image Retrieval: A Comprehensive User Interactive Simulation Tool for Endoscopic Image Databases

open access: yesApplied Medical Informatics, 2018
Until few years ago, radiological methods were widely used for the examination and investigation of the digestive tract. Today, wireless capsule endoscopy represents an innovative, noninvasive, effective solution that does not imply a risk of irradiation.
Roxana Andreea BĂLAN   +2 more
doaj  

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

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