Results 91 to 100 of about 74,634 (284)

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Diagnosis and outcome of oesophageal Crohn's disease [PDF]

, 2019
BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement.
Beaton, D, Chaparro, M, Ellul, P, Katsanos, K, Oliveira, AM, et al., Rodrigues, R, Savarino, E, Sladek, M, Teich, N, van der Woude, J, Vavricka, R, Wei, J   +11 more
core   +1 more source

The Effectiveness of Anti‐Adhesion Barriers on Prevention of Postoperative Adhesive Bowel Obstruction: Disease‐Free Survival Analysis

Annals of Gastroenterological Surgery, EarlyView.
We performed a survival analysis of abdominal gastroenterological cancer surgery cases with and without anti‐adhesive barriers, with the development of adhesive bowel obstruction as the outcome. The incidence of adhesive bowel obstruction was significantly lower in patients undergoing open or laparoscopic colorectal surgery in the anti‐adhesive ...
Shota Ebinuma, Susumu Kunisawa, Daisuke Takada, Kiyohide Fushimi, Akinobu Taketomi, Yuichi Imanaka   +5 more
wiley   +1 more source

Arteriovenous Malformation Detected by Small Bowel Endoscopy

Case Reports in Gastroenterology, 2014
Gastrointestinal bleeding that originates in the small intestine is often difficult to diagnose. When successful diagnosis reveals a lesion that can be localized preoperatively, the laparoscopic approach is an appropriate and beneficial treatment ...
Takaaki Fujii, Hiroki Morita, Toshinaga Sutoh, Takahiro Takada, Soichi Tsutsumi, Hiroyuki Kuwano   +5 more
doaj   +1 more source

Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms [PDF]

, 2015
OBJECTIVE: In primary care, assessing which patients with bowel symptoms harbour significant disease (cancer, higher-risk adenoma or IBD) is difficult.
Allison, Allison, Atkin, Callum G Fraser, Castro, Chiang, Craig Mowat, Cubiella, Duffy, Francis A Carey, Fraser, Fraser, Hazazi, Högberg, Jayne Digby, Jellema, Judith A Strachan, Kaul, Kok, Lieberman, McDonald, McDonald, NICE Diagnostics guidance (DG11), Parente, Pavlidis, Rapi, Robert J C Steele, Robyn Wilson, Roseth, Sipponen, Terhaar sive Droste, van Rheenen, Young   +32 more
core   +3 more sources

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

Annals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki, Wataru Osumi, Kohei Taniguchi, Nahoko Kato‐Kogoe, Shoichi Sakaguchi, Shota Nakamura, Yoshiro Imai, Takashi Nakano, Takaaki Ueno, Sang‐Woong Lee   +9 more
wiley   +1 more source

Endoscopic Scores for Evaluation of Crohn's Disease Activity at Small Bowel Capsule Endoscopy: General Principles and Current Applications

GE: Portuguese Journal of Gastroenterology, 2016
The small bowel is affected in the vast majority of patients with Crohn's Disease (CD). Small bowel capsule endoscopy (SBCE) has a very high sensitivity for the detection of CD-related pathology, including early mucosal lesions and/or those located in ...
Bruno Rosa, Rolando Pinho, Susana Mão de Ferro, Nuno Almeida, José Cotter, Miguel Mascarenhas Saraiva   +5 more
doaj   +1 more source

Systematic Review and Meta‐Analysis of Short‐ and Long‐Term Outcomes Following Natural Orifice Specimen Extraction for Colon Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Natural orifice specimen extraction (NOSE) in colon cancer surgery raises concerns about intra‐abdominal infection, peritoneal seeding, and local recurrence due to possible tumor cell implantation. This systematic review and meta‐analysis compares complete intracorporeal resection with NOSE versus conventional laparoscopic colon ...
Daichi Kitaguchi, Antonello Forgione, Mariano Giménez, Tatsuya Oda, Jacques Marescaux   +4 more
wiley   +1 more source

Age Is a Risk Factor for Gastroscopy-Assisted Capsule Endoscopy in Children

The Turkish Journal of Gastroenterology
Background/Aims: The aim of this study was to explore the risk factors for the incidence of gastroscopy-assisted capsule endoscopy and the small bowel transit time in pediatric patients who underwent capsule endoscopy examination.
Jing Xie , Lu Ren , Defeng Liang, Liya Xiong, Liying Liu, Wanfu Xu, Sitang Gong, Lanlan Geng, Peiyu Chen, Hongli Wang   +9 more
doaj   +1 more source