Results 141 to 150 of about 74,634 (284)

Organ‐sparing strategies in patients with MSI/dMMR tumors including Lynch syndrome: Current state of the art and future perspectives for clinical decision‐making

International Journal of Cancer, EarlyView.
Abstract Deficiency in DNA mismatch repair (dMMR) is a common pathway of carcinogenesis across different tumor types and confers a characteristic microsatellite instability‐high (MSI‐H) molecular phenotype. The MSI‐H/dMMR phenotype may arise from an inherited pathogenic variant in the context of Lynch syndrome and is most frequently observed in ...
Martin Duval, Antoine Dardenne, Thomas Samaille, Leo Mas, Jérémie H. Lefèvre, Xavier Dray, Mathilde Wagner, Romain Cohen, Thierry André   +8 more
wiley   +1 more source

Beyond a Conduit: The Evolution of Functional Biliary Stents From Active Intervention to Enabling Platforms

iNew Medicine, EarlyView.
This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li, Xu Liu, Xin Ye, Zhixia Dong, Xinjian Wan   +4 more
wiley   +1 more source

Clinical Implications of Ki‐67 Index, Grade and Hormonal Changes in Pancreatic Neuroendocrine Tumors: Insights Into Tumor Heterogeneity Based on Primary and Secondary Lesions

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Pancreatic neuroendocrine tumors (PanNETs) show heterogeneity, including temporal shifts in proliferation and hormone production; however, their clinical implications remain uncertain. Methods This retrospective study included 114 patients with metastatic or recurrent PanNETs at Kyushu University Hospital.
Masatoshi Murakami, Nao Fujimori, Kazuhide Matsumoto, Keijiro Ueda, Kohei Nakata, Masafumi Nakamura, Takeo Yamamoto, Yoshinao Oda, Tetsuhide Ito, Yoshihiro Ogawa   +9 more
wiley   +1 more source

Surrogate measure of gut blood flow via superior mesenteric circulation on ultrasound in adults who underwent esophagectomy: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Early enteral nutrition is recommended for critically ill patients. However, feeding an ischemic gastrointestinal tract with enteral nutrition may lead to gut necrosis. Although gut tolerance of enteral nutrition is assessed by various symptoms, none of them provide conclusive evidence of gut ischemia. We investigated the blood flow
Tomonori Narita, Kazuhiko Fukatsu, Reo Inoue, Satoshi Murakoshi, Midori Noguchi, Nana Matsumoto, Shoh Yajima, Koichi Yagi, Yoshifumi Baba   +8 more
wiley   +1 more source

Capsule endoscopy in the diagnosis of Crohn’s disease

Medical Devices: Evidence and Research, 2013
Yaron NivDepartment of Gastroenterology, Rabin Medical Center, Tel Aviv University, Petah Tikva, IsraelAbstract: Crohn’s disease is a chronic inflammatory disorder affecting any part of the gastrointestinal tract, but frequently involves the small ...
Niv Y
doaj  

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner, Amit Assa, Mikkel Malham, Shira Yuval Bar‐Asher, Carla Rayan, Jeffrey S. Hyams, Holm H. Uhlig, Brad Pasternak, David C. Wilson, Hilary K. Michel, Lissy de Ridder, Eric Zuckerman, Marina Aloi, Peter Szitanyi, Marla C. Dubinsky, Anne M. Griffiths, Roberto Saldana, Javier Martín‐de‐Carpi, Eytan Wine, Richard K. Russell, Jeremy Adler, Joseph Picoraro   +21 more
wiley   +1 more source

Post Capsule Endoscopy Small Bowel Cancer Rate-An Australian Data Linkage Analysis. [PDF]

J Gastrointest Cancer
Hoey P, Goetz N, Ryan K, Appleyard M, Grimpen F.   +4 more
europepmc   +1 more source

[Small bowel capsule endoscopy].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 2011
Capsule endoscopy enables inspection of the gastrointestinal tract without discomfort or need for sedation and thus obviates the risks associated with traditional endoscopy. This review presents an update on small bowel capsule endoscopy since its introduction in 2001.
openaire   +1 more source

Adequate vitamin D is associated with favorable disease outcome in children with inflammatory bowel disease receiving anti‐tumor necrosis factor alpha therapy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Deficiency of serum 25‐hydroxyvitamin D [25(OH)D] was associated with decreased short‐term response to anti‐tumor necrosis factor‐alpha (TNF‐α) agents in adults with inflammatory bowel disease (IBD). The aim of this study was to evaluate the association between serum 25(OH)D levels and the outcome of children with IBD undergoing ...
Adi Anafy, Yaara Manor, Maayan Shemer, Reut Doyev, Eytan Damari, Shlomi Cohen, Anat Yerushalmy‐Feler   +6 more
wiley   +1 more source

Real‐world data on STRIDE‐II treatment targets in a pediatric cohort with inflammatory bowel disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives STRIDE (selecting therapeutic targets in inflammatory bowel disease) established evidence‐based targets for treat‐to‐target strategies in IBD. STRIDE‐II designates clinical remission, C‐reactive protein (CRP) normalization, and fecal calprotectin (FC) reduction as short‐ to intermediate‐term targets, and mucosal healing as a long ...
Marie‐Luise Frank, Thu Giang Le Thi, Ina Schacker, Lena Bragagna, Milena Geist, Simon Buehler, Victoria Riedl, Sibylle Koletzko, Tobias Schwerd, Hannes Hoelz   +9 more
wiley   +1 more source