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Smoking and endothelial function
Progress in Cardiovascular Diseases, 2003The arterial endothelium is a vital homeostatic cell layer responsible for a variety of functions such as thromboresistance, control of vessel tone, and vessel growth. Recent evidence has indicated that both active and passive cigarette smoking are associated with dysfunction of normal endothelial physiology, in a dose dependent and potentially ...
Rajesh, Puranik, David S, Celermajer
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Endothelial function and atherosclerosis
Coronary Artery Disease, 1999Under normal conditions, the vascular endothelium exerts vasodilator, antithrombotic, and growth-inhibiting effects on the vessel wall. In the setting of atherosclerosis, endothelial dysfunction contributes to vasoconstriction, thrombosis, and growth of vascular smooth muscle. This article reviews the important contributors to endothelial function both
E S, Biegelsen, J, Loscalzo
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Endothelial function and hypertension
Current Opinion in Cardiology, 2007Endothelial dysfunction, in particular a reduced vascular availability of endothelium-derived nitric oxide, has been analysed in numerous experimental and clinical studies as a potential mechanism mediating the adverse vascular effects of hypertension.
Ulf, Landmesser, Helmut, Drexler
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Protection of Endothelial Function
2005The vascular endothelium synthesizes and releases a spectrum of vasoactive substances and therefore plays a fundamental role in the basal and dynamic regulation of the circulation. Nitric oxide (NO)--originally described as endothelium-derived relaxing factor--is released from endothelial cells in response to shear stress produced by blood flow, and in
Spieker LE, Lüscher TF
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Drugs, 1997
The endothelium is involved in both the physiological regulation of vascular tone and the structural transformation of the vessel under pathological conditions. Under physiological conditions, endothelial cells continuously secrete nitric oxide (NO), which relaxes smooth muscle cells and ensures vessel patency.
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The endothelium is involved in both the physiological regulation of vascular tone and the structural transformation of the vessel under pathological conditions. Under physiological conditions, endothelial cells continuously secrete nitric oxide (NO), which relaxes smooth muscle cells and ensures vessel patency.
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Measuring endothelial function
Current Diabetes Reports, 2006Dysfunction of the endothelium and of the arterial wall is well described in patients with atherosclerosis, diabetes, and other risk factors for vascular disease. In recent years, clinical research has focused on elucidating the role of this dysfunction in influencing vascular disease progression.
Christopher J, Lockhart +2 more
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Endothelial functions in Behçet’s disease
Rheumatology International, 2005Behçet's disease (BD) is a systemic vasculitis, capable of involving all types of vessels. Endothelial dysfunction (ED) has been previously documented in BD. The aim of the study was to see whether ED was more prominent in Behçet's patients with vascular involvement (VI) than in those without.
Kayikçioglu M. +6 more
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2006
It has been shown that the presence of well-preserved brachial artery vasoreactivity predicts the absence of coronary artery disease. The recent findings that coronary endothelial dysfunction is associated with an increased risk of stroke or transient ischemic attack in middle-aged patients without coronary artery disease support the concept that ...
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It has been shown that the presence of well-preserved brachial artery vasoreactivity predicts the absence of coronary artery disease. The recent findings that coronary endothelial dysfunction is associated with an increased risk of stroke or transient ischemic attack in middle-aged patients without coronary artery disease support the concept that ...
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Exercise and endothelial function
Coronary Artery Disease, 2000Regular exercise has many benefits for health and has been found to result in a lower incidence of cardiac events and mortality. The exact mechanism is not known; however, physical activity improves cardiac risk factor profiles and may also lead to an improvement in endothelial function.
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Journal of Cellular Physiology, 2003
AbstractEndothelial cells play a wide variety of critical roles in the control of vascular function. Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure as well as of the functional properties of the endothelial cells shifted their role from a passive membrane or barrier to a complex tissue with complex functions
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AbstractEndothelial cells play a wide variety of critical roles in the control of vascular function. Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure as well as of the functional properties of the endothelial cells shifted their role from a passive membrane or barrier to a complex tissue with complex functions
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