Results 191 to 200 of about 1,271,424 (340)

1122-165 Dimerization of mitrogen-activated protein kinase and auto-phosphorylation of akt occur in the newly differentiated endothelial-like cells from adult bone marrow stem cells in vitro

, 2004
Zhenguo Liu, Rong Lou, Yuehua Jing, Kapla Gupta, Catherine M. Verfaillie, Robert J. Bache   +5 more
openalex   +1 more source

The combination of granulocyte colony-stimulating factor and stem cell factor significantly increases the number of bone marrow–derived endothelial cells in brains of mice following cerebral ischemia [PDF]

, 2008
Zsuzsanna Tóth, Ronen R. Leker, Tal Shahar, Sandra Pastorino, Ildikó Szalayova, Brook Asemenew, Sharon Key, Alissa Parmelee, Balázs Mayer, Krisztián Németh, András Bratincsák, Éva Mezey   +11 more
openalex   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Transplantation of human embryonic stem cell‐derived endothelial cells for vascular diseases [PDF]

, 2008
Zongjin Li, Zhongchao Han, Joseph C. Wu
openalex   +1 more source

Human Vascular Tissue Models Formed from Human Induced Pluripotent Stem Cell Derived Endothelial Cells

Stem Cell Reviews and Reports, 2014
David G. Belair, Jordan Whisler, Jorge Valdez, Jeremy Velazquez, James A. Molenda, Vernella Vickerman, Rachel L. Lewis, C. Daigh, Tyler D. Hansen, D. A. Mann, J. Thomson, L. Griffith, R. Kamm, Michael P. Schwartz, W. Murphy   +14 more
semanticscholar   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Wnt5a Is Required for Endothelial Differentiation of Embryonic Stem Cells and Vascularization via Pathways Involving Both Wnt/β-Catenin and Protein Kinase Cα [PDF]

, 2008
Donghwa Yang, Juyong Yoon, Soung-Hoon Lee, Vı́tězslav Bryja, Emma Andersson, Ernest Arenas, Young‐Guen Kwon, Kang‐Yell Choi   +7 more
openalex   +1 more source

Engineered MSC Aggregates with E/N‐Cadherin and IL‐6 Preconditioning for the Treatment of Systemic Sclerosis

Advanced Healthcare Materials, EarlyView.
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang, Mengyuan Qian, Yirui Shi, Jiaxu Cao, Min Xu, Xin Wen, Yunxia Yan, Sha Liu, Hongwei Chen, Shanshan Liu, Jun Yang, Lingyun Sun   +11 more
wiley   +1 more source

Shear stress-triggered adenosine triphosphate regulates angiogenic properties of human periodontal ligament stem cells. [PDF]

Sci Rep
Kyawsoewin M, Manokawinchoke J, Termkwanchareon C, Lwin HY, Yaklai S, Limjeerajarus N, Limjeerajarus CN, Egusa H, Osathanon T, Limraksasin P.   +9 more
europepmc   +1 more source

Loss of Tie2 receptor compromises embryonic stem cell–derived endothelial but not hematopoietic cell survival

, 2005
Isao Hamaguchi, Tohru Morisada, Masaki Azuma, Kyoko Murakami, Madoka Kuramitsu, Takuo Mizukami, Kazuyuki Ohbo, Kazunari Yamaguchi, Yuichi Oike, Daniel Dumont, Toshio Suda   +10 more
openalex   +1 more source