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Endothelin-1 in systemic sclerosis
Reumatismo, 2011 We evaluated endothelin-1 (ET-1) plasma levels in patients affected by primary Raynaud’s phenomenon (PRP), as well as in patients with systemic sclerosis (SSc) and secondary Raynaud’s phenomenon (SRP).
C. Pizzorni +3 more
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Sodium intake and biological sex influence urinary endothelin-1 in salt-resistant adults: a pilot study. [PDF]
Am J Physiol Regul Integr Comp PhysiolNasci VL +9 more
europepmc +3 more sources
Endothelin-1 in systemic sclerosis
Indian Dermatology Online Journal, 2012 Introduction: Scleroderma is a systemic disorder with unknown etiology most notably characterized by skin thickening and organ damage. Endothelin-1 (ET-1) plays a role in skin fibrosis.
Mehrdad Aghaei +7 more
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Circulating Levels of Endothelin-1 and Big Endothelin-1 in Patients with Essential Hypertension
Pathophysiology, 2021 The role of endothelin-1 (ET-1) in the pathogenesis of hypertension (HTN) is not clearly established. There is evidence that its circulating levels are elevated in some forms of experimental and human HTN, but this was not a consistent finding.
Krasimir Kostov, Alexander Blazhev
doaj +1 more source
Східноукраїнський медичний журнал, 2021 Endothelial dysfunction is considered one of the main mechanisms for the further development of arterial hypertension (AH) and its complications, and endothelin-1 (ЕТ-1) plays one of the key roles in this process.
Yu. O. Smiianova
doaj +1 more source
Endocan, ET-1, and ETAR Expression Profiles in Unicystic Ameloblastoma, Multicystic Ameloblastoma, and Ameloblastic Carcinoma [PDF]
Middle East Journal of Cancer, 2019 Background: Odontogenic lesions range from simple cysts to benign tumors and carcinomas. Unicystic ameloblastoma is a monocystic lesion and a less aggressive tumor compared to multicystic ameloblastoma.
Soussan Irani, Zhaleh Mohsenifar
doaj +1 more source
Spironolactone rescues Dot1a-Af9-mediated repression of endothelin-1 and improves kidney injury in streptozotocin-induced diabetic rats. [PDF]
PLoS ONE, 2012 The molecular mechanism linking aldosterone and endothelin-1 in the development of diabetic nephropathy has not been completely elucidated. Here, we provide evidence showing that streptozotocin-induced diabetic rats have significantly increased ...
Qiaoling Zhou +10 more
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Pulmonary Circulation, 2023 Activin A, a member of TGF‐β superfamily, has been implicated in the pathogenesis of pulmonary artery hypertension (PAH). PAH due to congenital heart disease (CHD‐PAH) is a major problem in developing countries.
Muhammad R. Hadwiono +6 more
doaj +1 more source
Endothelins as mediators in the modulation of cardiac performance [PDF]
Praxis Medica, 2014 The role of endothelin in cardiovascular physiology and pathophysiology has been undeniable ever since its discovery. Endothelins in the heart are important for the development, growth and remodeling, as well as for the control of contractility and ...
Smiljić Sonja +4 more
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Endothelium-derived endothelin-1 [PDF]
Pflügers Archiv - European Journal of Physiology, 2009 One year after the revelation by Dr. Furchgott in 1980 that the endothelium was obligatory for acetylcholine to relax isolated arteries, it was clearly shown that the endothelium could also promote contraction. In 1988, Dr. Yanagisawa's group identified endothelin-1 (ET-1) as the first endothelium-derived contracting factor.
Thorin, Eric, Webb, David J.
openaire +3 more sources