Results 11 to 20 of about 23,650,103 (189)
Identification of endothelin-1, endothelin-2 and endothelin-3 in human endometrium [PDF]
Reproduction, 1993 This study determined the presence of specific endothelin isoforms in human endometrium using high performance liquid chromatography (HPLC) combined with radioimmunoassay, and immunocytochemistry to detect the endothelin precursors (proendothelin-1, proendothelin-2 and proendothelin-3).
Christopher Plumpton +5 more
openaire +4 more sources
Endothelin-1 (1-31) Is an Intermediate in the Production of Endothelin-1 After Big Endothelin-1 Administration In Vivo [PDF]
Hypertension, 2005 The precursor of endothelin-1, big endothelin-1, can be hydrolyzed by chymase to generate endothelin-1 (1-31) in vitro. In the present study, we explored the processes involved in the production of endothelin-1 (1-31) as well as its pharmacodynamic characteristics in the rabbit in vivo.
Julie Labonté +5 more
openaire +3 more sources
Immunohistochemical Localization of Endothelin- 1 and Endothelin A Receptor in Human Primary Tooth Enamel Organ [PDF]
Journal of Dentistry, 2023 Statement of the Problem: Enamel organ (EO) is an ectodermal derived structure, which is involved in the different aspects of tooth development. Tooth development shares the same regulatory molecules and genes expressed in other developing organs ...
Soussan Irani +2 more
doaj +1 more source
Production of endothelin‐1 and big‐endothelin‐1 by pleural mesothelial cells [PDF]
FEBS Letters, 1992 Immunoreactive endothelin‐1 (ET‐1) and big‐endothelin‐1 (big‐ET‐1) were detected in conditioned medium of cultured rat pleural mesothelial cells by using sensitive sandwich‐type enzyme immunoassays. The amount of both ET‐1 and big‐ET‐1 increased time‐dependently. In both instances, maximal amount was detectable in conditioned medium obtained after 72 h
Maki Kuwahara +2 more
openaire +2 more sources
Analysis of Endothelin-1 Concentrations in Individuals with Periodontitis
Scientific Reports, 2020 Endothelin 1 (ET-1) has been shown to have a key role in homeostasis and function of endothelium and maybe fundamental in the relationship between coronary heart disease (CHD) and periodontitis.
G. Isola +4 more
semanticscholar +1 more source
Spironolactone rescues Dot1a-Af9-mediated repression of endothelin-1 and improves kidney injury in streptozotocin-induced diabetic rats. [PDF]
PLoS ONE, 2012 The molecular mechanism linking aldosterone and endothelin-1 in the development of diabetic nephropathy has not been completely elucidated. Here, we provide evidence showing that streptozotocin-induced diabetic rats have significantly increased ...
Qiaoling Zhou +10 more
doaj +1 more source
Analiz Riska Zdorovʹû, 2021 Our research goal was to reveal peculiarities related to changes in endothelin-1 contents in blood serum in young and middle-aged people exposed to occupational noise and industrial welding and silicon-containing aerosols with fibrogenic effects. Another
I.A. Umnyagina +5 more
doaj +1 more source
Definitions, 2020 Endothelin-1 receptor (427 aa, ~49 kDa) is encoded by the human EDNRA gene. This protein is a multipass transmembrane protein that is a receptor for endothelin-1 protein and plays a role in G protein-mediated signal transduction.
semanticscholar +1 more source
Pulmonary Circulation, 2023 Activin A, a member of TGF‐β superfamily, has been implicated in the pathogenesis of pulmonary artery hypertension (PAH). PAH due to congenital heart disease (CHD‐PAH) is a major problem in developing countries.
Muhammad R. Hadwiono +6 more
doaj +1 more source
Serum endothelin-1 level positively correlates with waist and hip circumferences in stable coronary artery disease patients [PDF]
Reviews in Cardiovascular Medicine, 2021 Central obesity is associated with increased level and activity of endothelin-1. The waist and hip circumferences are simple indicators of central obesity.
Anggoro Budi Hartopo +3 more
doaj +1 more source