Plasma endothelin-1 levels in patients with rotator cuff tear: a case-control study. [PDF]
Gumina S +7 more
europepmc +1 more source
Cardiovascular biomarkers and preeclampsia: A narrative review
Preeclampsia (PE) is a complex pregnancy disorder linked to cardiovascular disease (CVD) through shared risk factors and epidemiological associations. Cardiovascular biomarkers are valuable for predicting, diagnosing and assessing PE, as well as estimating future CVD risk. This review explores current cardiovascular biomarkers used in clinical practice
Johana Ullmo +8 more
wiley +1 more source
A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa +7 more
wiley +1 more source
Correction to: The dual endothelin-1 antagonist aprocitentan alleviates mitochondrial oxidative stress in human cardiac fibroblasts. [PDF]
europepmc +1 more source
ABSTRACT Aim Genetic connectivity and local adaptation were examined across the distribution of the freshwater sponge Ephydatia muelleri. Because it occupies an exceptional breadth of freshwater environments across a broad geographic range, this species offers key insights into biogeographic processes shaping genetic structure and adaptation in inland ...
Laura de la Cruz‐Castillejo +18 more
wiley +1 more source
New rat model of spinal cord infarction with long-lasting functional disabilities generated by intraspinal injection of endothelin-1. [PDF]
Otani M +12 more
europepmc +1 more source
ABSTRACT Aortic dissection is a life‐threatening cardiovascular emergency with limited pharmacological options. This study focuses on elucidating the multi‐target and multi‐pathway mechanisms through which morusin mitigates aortic dissection progression, integrating network pharmacology, single‐cell transcriptomics and experimental validation.
Zhaomeng Wang +10 more
wiley +1 more source
Plasma Extracellular Vesicles from Preeclamptic Patients Trigger a Detrimental Crosstalk Between Glomerular Endothelial Cells and Podocytes Involving Endothelin-1. [PDF]
Grossini E +15 more
europepmc +1 more source
Current Status of Research on Losartan in Tumour Therapy
ABSTRACT Losartan, a widely prescribed antihypertensive agent, has attracted growing interest as a potential adjuvant in cancer therapy due to its affordability, established safety profile and pleiotropic effects. Emerging preclinical evidence demonstrates that losartan can effectively modulate the tumour microenvironment (TME) by inhibiting ...
Han Wang, Shuang Yuan, Hongjing Wang
wiley +1 more source

