Results 21 to 30 of about 141,025 (360)
Vestnik Dermatologii i Venerologii, 2021 Background. Atopic dermatitis is a chronic multifactorial dermatosis with a complex pathophysiological basis. One of the poorly studied links in the pathogenesis of the disease is endothelin-1.
Irina V. Kibalina, Namzhil N. Tsybikov
doaj +1 more source
Immunohistochemical Localization of Endothelin- 1 and Endothelin A Receptor in Human Primary Tooth Enamel Organ [PDF]
Journal of Dentistry, 2023 Statement of the Problem: Enamel organ (EO) is an ectodermal derived structure, which is involved in the different aspects of tooth development. Tooth development shares the same regulatory molecules and genes expressed in other developing organs ...
Soussan Irani +2 more
doaj +1 more source
Journal of Pharmacological Sciences, 2003 We examined the effect of endothelin-1, endothelin-3 and sarafotoxin S6c on the release of noradrenaline from gastric sympathetic nerve terminals using an isolated, vascularly perfused rat stomach.
Kumiko Nakamura +2 more
doaj +1 more source
Frontiers in Immunology, 2023 Major Histocompatibility Complex (MHC) molecules have been proposed to play a role in Sickle Cell Disease (SCD) pathophysiology. Endothelial cells express MHC molecules following exposure to cytokines.
Yaritza Inostroza-Nieves +6 more
doaj +1 more source
Evidence for G‐Protein–Coupled Estrogen Receptor as a Pronatriuretic Factor
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background The novel estrogen receptor, G‐protein–coupled estrogen receptor (GPER), is responsible for rapid estrogen signaling. GPER activation elicits cardiovascular and nephroprotective effects against salt‐induced complications, yet there is no ...
Eman Y. Gohar +11 more
doaj +1 more source
Endocrine and Metabolic Science, 2023 Introduction: African Americans (AAs) have the highest prevalence of hypertension among United States racial/ethnic groups. Regulators of blood pressure, such as aldosterone and endothelin-1, impact glucose regulation.
Joshua J. Joseph +7 more
doaj +1 more source
Portopulmonary hypertension practice patterns after liver transplantation
Liver Transplantation, EarlyView., 2022 Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose +3 more
wiley +1 more source
Tumor Biology, 2017 Patients with esophageal squamous cell carcinoma have poor survival and high recurrence rate, thus an effective prognostic biomarker is needed. Endothelin-converting enzyme-1 is responsible for biosynthesis of endothelin-1, which promotes growth and ...
Ching-Fang Wu +6 more
doaj +1 more source
Mitochondrial Fission Inhibitors Suppress Endothelin-1-Induced Artery Constriction
Cellular Physiology and Biochemistry, 2017 Background/Aims: Endothelin-1 is implicated in the pathogenesis of hypertension, but the underlying mechanisms remained elusive. Our previous study found that inhibition of mitochondrial fission of smooth muscle cells suppressed phenylephrine- and high K+
Chang Chen +11 more
doaj +1 more source
Contribution of Piezo2 to endothelium-dependent pain. [PDF]
, 2015 BackgroundWe evaluated the role of a mechanically-gated ion channel, Piezo2, in mechanical stimulation-induced enhancement of hyperalgesia produced by the pronociceptive vasoactive mediator endothelin-1, an innocuous mechanical stimulus-induced ...
Bogen, Oliver +3 more
core +2 more sources