Results 21 to 30 of about 23,650,103 (189)
Vestnik Dermatologii i Venerologii, 2021 Background. Atopic dermatitis is a chronic multifactorial dermatosis with a complex pathophysiological basis. One of the poorly studied links in the pathogenesis of the disease is endothelin-1.
Irina V. Kibalina, Namzhil N. Tsybikov
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Endothelins as mediators in the modulation of cardiac performance [PDF]
Praxis Medica, 2014 The role of endothelin in cardiovascular physiology and pathophysiology has been undeniable ever since its discovery. Endothelins in the heart are important for the development, growth and remodeling, as well as for the control of contractility and ...
Smiljić Sonja +4 more
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Gene Expression of Endothelin-1, Endothelin-Converting Enzyme-1, and Endothelin Receptors in Human Epididymis1 [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1997 We have previously reported the presence of endothelin-1 (ET-1) and its receptors in the human testis. In the present study we extended our investigations to human epididymis. The rationale of our study originated from the fact that sperm appear to be immotile during their transit through the epididymis.
PERI, ALESSANDRO +10 more
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Frontiers in Immunology, 2023 Major Histocompatibility Complex (MHC) molecules have been proposed to play a role in Sickle Cell Disease (SCD) pathophysiology. Endothelial cells express MHC molecules following exposure to cytokines.
Yaritza Inostroza-Nieves +6 more
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An emerging role for microRNA in the regulation of endothelin-1
Frontiers in Physiology, 2013 Endothelin-1 (ET-1) is a peptide signaling molecule serving diverse functions in many different tissues such as the vasculature and the kidney. The primary mechanism thought to control ET-1 bioavailability is the rate of transcription from the ET-1 gene (
Mollie E Jacobs +3 more
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Comparison of haemoconcentration induced by big endothelin‐1 and endothelin‐1 in mice [PDF]
British Journal of Pharmacology, 1993 The profile of haemoconcentration induced by big endothelin‐1 (big ET‐1), a precursor of endothelin‐1 (ET‐1), was compared with that induced by endothelin‐1 in mice. ET‐1(1.5 nmol kg−1, i.v.) increased haematocrit in mice, which reached a maximum at 5 min and then returned to the control value within 30 min after the administration, this occurred at ...
Rieko Asakura +6 more
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Endothelin-converting enzyme-1 expression in acute and chronic liver injury in fibrogenesis
Animal Cells and Systems, 2019 Endothelin-1 (ET-1) induces contraction, proliferation, and collagen synthesis of activated hepatic stellate cells and is a potent mediator of portal hypertension.
Tae-Jun Cho, Hyo-Jung Kim, Jaejin Cho
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Endothelin-1 is associated with fibrosis in proliferative diabetic retinopathy membranes. [PDF]
PLoS ONE, 2018 To characterize the relationship between endothelin-1 and fibrosis in epiretinal membranes in proliferative diabetic retinopathy and explore the role of endothelial-mesenchymal transition in these membranes.Membranes were obtained from eyes undergoing ...
William Chang +2 more
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Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx.
Journal of the American Society of Nephrology, 2016 Diabetic nephropathy (DN) is the leading cause of CKD in the Western world. Endothelin receptor antagonists have emerged as a novel treatment for DN, but the mechanisms underlying the protective effect remain unknown.
M. Garsen +9 more
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Tumor Biology, 2017 Patients with esophageal squamous cell carcinoma have poor survival and high recurrence rate, thus an effective prognostic biomarker is needed. Endothelin-converting enzyme-1 is responsible for biosynthesis of endothelin-1, which promotes growth and ...
Ching-Fang Wu +6 more
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