Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats [PDF]
<p><b>Background and Purpose:</b> The study aim was to assess the effects of magnesium sulfate (MgSO4) administration on white matter damage in vivo in spontaneously hypertensive rats.</p> <p><b>Methods:</b> ...
Gallagher, L. +8 more
core +1 more source
Expression of endothelin-1 in unaffected colon mucosa 10 cm and 20 cm from colorectal carcinoma [PDF]
Introduction: Endothelin-1 is a vasoconstrictor peptide primarily synthesized by endothelial and smooth muscle cells. Increased expression of this peptide has been observed in inflammation, hypoxia, ischemia, various cardiovascular diseases and various ...
Stanojlović Anja, Despotović Sanja
doaj +1 more source
Anti-adrenergic effects of endothelin on human atrial action potentials are potentially anti-arrhythmic [PDF]
Endothelin-1 (ET-1) is elevated in patients with atrial fibrillation (AF) and heart failure. We investigated effects of ET-1 on human atrial cellular electrophysiological measurements expected to influence the genesis and maintenance of AF.
Kane, K.A. +3 more
core +1 more source
Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]
No abstract ...
Berry, C +6 more
core +2 more sources
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Drug treatment of hypertension: focus on vascular health [PDF]
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C. +2 more
core +1 more source
In the literature cases of stroke and transient neurological symptoms have been described after sclerotherapy for chronic venous disease The initial interpretation of these phenomena was that of a micro air embolism in association with a patent foramen ...
Alessandro Frullini +9 more
doaj +1 more source
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat. [PDF]
BACKGROUND:Coronary artery remodelling and vasospasm is a complication of acute myocardial ischemia and reperfusion. The underlying mechanisms are complex, but the vasoconstrictor peptide endothelin-1 is suggested to have an important role.
Gry Freja Skovsted +5 more
doaj +1 more source
Endothelin-1 (1-31) Is an Intermediate in the Production of Endothelin-1 After Big Endothelin-1 Administration In Vivo [PDF]
The precursor of endothelin-1, big endothelin-1, can be hydrolyzed by chymase to generate endothelin-1 (1-31) in vitro. In the present study, we explored the processes involved in the production of endothelin-1 (1-31) as well as its pharmacodynamic characteristics in the rabbit in vivo.
Marie-Hélène, Fecteau +5 more
openaire +2 more sources
The Structural Features of Vascular Endothelium in Acute Cerebral Ischemia [PDF]
The aim of the research was to study the number and structural properties of desquamated endothelial cells (DECs) in the peripheral blood in carotid ischemic stroke (CIS) and carotid transient ischemic attacks (TIAs) and its connection with the marker of
Kosheleva, A. (Anna)
core +2 more sources

