Results 51 to 60 of about 141,025 (360)

Evaluation of the Expression Levels of Endothelin-1 and its Receptor (ETAR) in Dental Lamina during Different Stages of Development of Human Fetal Teeth

پزشکی بالینی ابن سینا, 2021
Background and Objective: Due to the significant importance of the teeth in mastication, speech, and aesthetics, it is necessary to identify all involved genes in the tooth development. Therefore, this study aimed to evaluate the role of endothelin-1 and
Soussan Irani, Shohreh Alimohammadi, Tahmineh Najafian   +2 more
doaj  

p90 ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq protein-coupled receptor stimuli, endothelin-1 and α1-adrenergic receptor agonists [PDF]

, 2012
Extracellular signal-regulated kinases 1/2 (ERK1/2) and their substrates, p90 ribosomal S6 kinases (RSKs), phosphorylate different transcription factors, contributing differentially to transcriptomic profiles.
Adachi, Angela Clerk, Bhatt, Bueno, Cargnello, Casar, Chen, Chen, Choi, Chuderland, Clerk, Clerk, Clerk, Clerk, Clerk, Clerk, Clerk, Cuello, Cullingford, Davies, Di, Doehn, Dokladda, Emre Amirak, Gao, Gillespie-Brown, Giraldo, Jensen, Kehat, Kennedy, Knepper, Lips, Lorenz, Marshall, Moor, Peter H. Sugden, Romeo, Sapkota, Stephen J. Fuller, Sugden, Sugden, Turjanski, Valks, Yue   +43 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Endothelial function vessel wall measures in patients with gout associated with coronary heart disease

Научно-практическая ревматология, 2007
Objective. To study function of endothelium in pts with gout associated with coronary heart disease (CHD) depending on hyperuricemia (HU) expression. Material and methods.
E S Feofanova, L A Knyaseva
doaj   +1 more source

Endothelin-1 contributes to the development of virus-induced demyelinating disease

Journal of Neuroinflammation, 2020
Background Experimental autoimmune encephalitis (EAE) and virally induced demyelinating disease are two major experimental model systems used to study human multiple sclerosis.
Young-Hee Jin, Bongsu Kang, Hyun S. Kang, Chang-Sung Koh, Byung S. Kim   +4 more
doaj   +1 more source

Changes in vasoactive pathways in congenital diaphragmatic hernia associated pulmonary hypertension explain unresponsiveness to pharmacotherapy [PDF]

, 2017
Background: Patients with congenital diaphragmatic hernia (CDH) have structural and functional different pulmonary vessels, leading to pulmonary hypertension.
Buscop-Van Kempen, M. (Marjon), Mous, D.S. (Daphne), Rottier, R.J. (Robbert), Tibboel, D. (Dick), Wijnen, R.M.H. (René)   +4 more
core   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Endothelin-1 Production by Normal Human Cultured Keratinocytes and its Regulation

Mediators of Inflammation, 1994
The possibility that cultured keratinocytes produce endothelins were investigated. The results showed that cultured keratinocytes derived from normal human skin produce endothelin-1. Moreover, keratinocyte endothelin-1 production was completely inhibited
Hajime Inoue, Nagaoki Wakisaka, Nobuhiro Tane, Kazumasa Ando, Emiko Isono, Miwa Yamanaka, Masaki Aihara, Hirotomo Ishida   +7 more
doaj   +1 more source

Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung disease [PDF]

, 2016
Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung ...
Amoroso, Daria, Barbano, Biagio, DI PAOLO, Marcello, Gigante, Antonietta, Palange, Paolo, Romaniello, Antonella, Rosato, Edoardo, Tallerini, Gaia   +7 more
core   +1 more source

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

Arthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis, Gerlando Natalello, Rossella De Angelis, Lucrezia Verardi, Dilia Giuggioli, Gianluigi Bajocchi, Lorenzo Dagna, Silvia Bellando‐Randone, Giovanni Zanframundo, Rosario Foti, Fabio Cacciapaglia, Giovanna Cuomo, Alarico Ariani, Edoardo Rosato, Gemma Lepri, Francesco Girelli, Valeria Riccieri, Elisabetta Zanatta, Ilaria Cavazzana, Francesca Ingegnoli, Maria De Santis, Giuseppe Murdaca, Giuseppina Abignano, Giorgio Pettiti, Alessandra Della Rossa, Maurizio Caminiti, Annamaria Iuliano, Giovanni Ciano, Lorenzo Beretta, Gianluca Bagnato, Ennio Lubrano, Maria Ilenia De Andres, Alessandro Giollo, Cosimo Bruni, Martina Orlandi, Marco Fornaro, Marta Saracco, Cecilia Agnes, Pier Giacomo Cerasuolo, Gabriella Alonzi, Edoardo Cipolletta, Federica Lumetti, Amelia Spinella, Luca Magnani, Corrado Campochiaro, Giacomo De Luca, Veronica Codullo, Elisa Visalli, Carlo Iandoli, Antonietta Gigante, Greta Pellegrino, Erika Pigatto, Maria‐Grazia Lazzaroni, Franco Franceschini, Elena Generali, Gianna Mennillo, Simone Barsotti, Giuseppa Pagano Mariano, Federica Furini, Licia Vultaggio, Simone Parisi, Clara Lisa Peroni, Gerolamo Bianchi, Enrico Fusaro, Gian Domenico Sebastiani, Marcello Govoni, Salvatore D'Angelo, Franco Cozzi, Fabrizio Conti, Serena Guiducci, Andrea Doria, Carlo Salvarani, Florenzo Iannone, Maria Antonietta D'Agostino, Clodoveo Ferri, Marco Matucci Cerinic, Silvia Laura Bosello, on behalf of SPRING collaborators   +77 more
wiley   +1 more source