Results 71 to 80 of about 23,650,103 (189)

Endothelin-1 level in scleroderma patients with and without fingertip pitting ulcer [PDF]

فصلنامه دانشگاه علوم پزشکی جهرم, 2011
Introduction:Scleroderma is a systemic disorder with unknown etiology most notably characterized by skin thickening and internal organ involvement. Endothelin-1 plays an important role in skin fibrosis.
Naser Aghdami, Abdorahman Rostamian, Sima Sedighi, Masoumeh Akhlaghi, Habib Zayeni, Farhad Gharibdost, Mehrdad Aghaei, Mahdieh Shojaa   +7 more
doaj  

Endothelin-1 Inhibits Apoptosis in Prostate Cancer

Neoplasia: An International Journal for Oncology Research, 2005
Endothelin-1 (ET-1), produced by the prostate epithelia, likely plays an important role in the progression of prostate cancer. ET-1 can bind two receptor subtypes; generally, binding of the endothelin receptor A (ETA) induces a survival pathway, whereas ...
Joel B. Nelson, Michael S. Udan, Georgi Guruli, Beth R. Pflug   +3 more
doaj   +1 more source

Dual endothelin-converting enzyme/neutral endopeptidase blockade in rats with D-galactosamine-induced liver failure

European Journal of Medical Research, 2011
Secondary activation of the endothelin system is thought to be involved in toxic liver injury. This study tested the hypothesis that dual endothelin-converting enzyme / neutral endopeptidase blockade might be able to attenuate acute toxic liver injury ...
Hocher B, Heiden S, von Websky K, Rahnenführer J, Kalk P, Pfab T   +5 more
doaj   +1 more source

Endothelin-1

Definitions, 2020

semanticscholar   +1 more source

Expression of Endothelin-1, Endothelin Receptor-A, and Endothelin Receptor-B in facial melasma compared to adjacent skin

Clinical, Cosmetic and Investigational Dermatology, 2023
Carolina Nunhez da Silva,1 Hélio Amante Miot,1 Tony Fernando Grassi,2 Luciane Alarcão Dias-Melício,2– 4 Leandro Santos,2,3 Ana Cláudia Cavalcante Espósito1 1Department of Dermatology, São Paulo State University (UNESP) - Medical School of Botucatu ...
da Silva CN, Miot HA, Grassi TF, Dias-Melício LA, Santos L, Espósito ACC   +5 more
doaj  

Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism

Neural Regeneration Research
[INLINE:1] Vascular etiology is the second most prevalent cause of cognitive impairment globally. Endothelin-1, which is produced and secreted by endothelial cells and astrocytes, is implicated in the pathogenesis of stroke.
Jie Li, Wen Jiang, Yuefang Cai, Zhenqiu Ning, Yingying Zhou, Chengyi Wang, Sookja Ki Chung, Yan Huang, Jingbo Sun, Minzhen Deng, Lihua Zhou, Xiao Cheng   +11 more
doaj   +1 more source

The endothelin system in pulmonary and renal vasculopathy: les liaisons dangereuses

European Respiratory Review, 2009
Endothelial cells regulate vascular tone largely by the actions of endothelin-1. Endothelin-1 is a potent vasoconstrictor, with effects that are dependent on the receptors to which it binds as well as their location.
J-L Vachiéry, A. Davenport
doaj  

Endothelin-1 Measurement

Definitions, 2020

semanticscholar   +1 more source

A review of sitaxsentan sodium in patients with pulmonary arterial hypertension

Vascular Health and Risk Management, 2007
Aaron B WaxmanDepartment of Internal Medicine, Pulmonary Critical Care Unit, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USAAbstract: Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which ...
Aaron B Waxman
doaj  

Dynamics of laboratory markers of endothelial dysfunction in patients with psoriatic arthritis under the influence of the interleukin-17A inhibitor netakimab

Современная ревматология
Objective: a comparative evaluation of the effect of the interleukin-17A inhibitor (iIL) netakimab (NTK) and methotrexate (MTX) on laboratory markers of endothelial dysfunction in patients with psoriatic arthritis (PsA) in comparison with the dynamics of
A. V. Petrov, O. A. Pritulo, A. A. Petrov   +2 more
doaj   +1 more source