Results 201 to 210 of about 2,437,403 (392)

Tranexamic Acid for Hyperpigmentation Disorders: A Literature Review on Efficacy and Safety in Melasma and PIH

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hyperpigmentation disorders, including melasma and post‐inflammatory hyperpigmentation (PIH), are common dermatologic conditions associated with significant cosmetic and psychological burden. Tranexamic acid (TXA), an antifibrinolytic agent, has gained increasing attention due to its anti‐inflammatory and antimelanogenic properties.
Ahmed AlJabr   +2 more
wiley   +1 more source

In vivo optoacoustic imaging of endothelin receptor expression and treatment response in the hypoxic tumor microenvironment. [PDF]

open access: yesEur J Nucl Med Mol Imaging
Höltke C   +7 more
europepmc   +1 more source

Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Mutations in GNAO1, the gene encoding Gαo, are associated with a wide range of neurodevelopmental disorders. In this study, we show that Gαo variants linked to the most severe patient phenotypes fail to disengage from activated Gi/o‐coupled GPCRs, thereby blocking GRK‐mediated receptor phosphorylation and internalization.
Yonika A. Larasati   +4 more
wiley   +1 more source

The role of endothelin receptor antagonists in kidney disease. [PDF]

open access: yesRen Fail
Ma X   +5 more
europepmc   +1 more source

ENDOTHELIN TYPE B RECEPTOR COULD BE ASSOCIATED WITH A PRO-CATABOLIC AND PRO-HYPERTROPHIC PHENOTYPE IN CHONDROCYTES [PDF]

open access: bronze
EL MAKHLOUFI Jaouhara   +8 more
openalex   +1 more source

Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco   +4 more
wiley   +1 more source

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