Results 211 to 220 of about 2,437,403 (392)

Endothelin Receptor-A Inhibition Decreases Ductular Reaction, Liver Fibrosis, and Angiogenesis in a Model of Cholangitis. [PDF]

Cell Mol Gastroenterol Hepatol, 2023
Owen T, Carpino G, Chen L, Kundu D, Wills P, Ekser B, Onori P, Gaudio E, Alpini G, Francis H, Kennedy L.   +10 more
europepmc   +1 more source

Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

Advanced Science, Volume 13, Issue 5, 27 January 2026.
This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li, Huizhi Sun, Jing Liu, Yan Wu, Lin Wei, Jianming Li, Yudong Yuan, Peng Xie, Chao Xu, Guolu Luo, Yuqi Guan, Yukuan Feng, Antao Chang, Jihui Hao, Chongbiao Huang   +14 more
wiley   +1 more source

Dual Endothelin Receptor Inhibition with Bosentan Does Not Prevent the Early Formation of Post-Traumatic Joint Contracture in a Rat Model. [PDF]

J Clin Med
Wegner E, Warnke D, Buschmann V, Hild B, Pirkl A, Ritz U, Harper A, Gercek E, Drees P, Baranowski A.   +9 more
europepmc   +1 more source

The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats. [PDF]

Front Ophthalmol (Lausanne), 2023
Kodati B, Zhang W, He S, Pham JH, Beall KJ, Swanger ZE, Krishnamoorthy VR, Harris PE, Hall T, Tran AV, Chaphalkar RM, Chavala SH, Stankowska DL, Krishnamoorthy RR.   +13 more
europepmc   +1 more source

Transgenic expression of the endothelin-B receptor prevents congenital intestinal aganglionosis in a rat model of Hirschsprung disease. [PDF]

, 1998
Cheryl E. Gariepy, S. Clay Williams, James A. Richardson, Robert E. Hammer, Masashi Yanagisawa   +4 more
openalex   +1 more source

Immunotherapy and endothelin receptor antagonists for treatment of castration‐resistant prostate cancer

International Journal of Cancer, 2013
N. Shao*, Yang Wang, W. Jiang, D. Qiao, Shi-ge Zhang, Ye Wu, Xiang Xiang Zhang, Jiufeng Wang, Yi Ding, N. Feng   +9 more
semanticscholar   +1 more source

Central blood volume in cirrhosis [PDF]

, 1993
Bendtsen, Flemming, Gerbes, Alexander L., Henriksen, Jens H.   +2 more
core   +1 more source

Essential Updates 2024/2025: History, Pathogenesis, Definition, Prevention, and Management of Small‐for‐Size Syndrome in Living‐Donor Liver Transplantation

Annals of Gastroenterological Surgery, Volume 10, Issue 1, Page 35-41, January 2026.
ABSTRACT Although living‐donor liver transplantation (LDLT) has become the standard treatment for end‐stage liver disease, one of its major challenges is small‐for‐size syndrome (SFSS). SFSS is characterized by severe icterus and intractable ascites, although the severity of the condition can vary.
Toru Ikegami, Masashi Tsunematsu, Shinji Onda, Kenei Furukawa, Koichiro Haruki, Michinori Matsumoto, Yoshihiro Shirai   +6 more
wiley   +1 more source

HJP 272, an endothelin receptor antagonist, and its role in cancer cell migration and invasion. [PDF]

Transl Oncol
Baig N, Chilamakuri R, Agarwal S, Muth A, Reznik SE.   +4 more
europepmc   +1 more source

Insulin resistance, kidney outcomes and effects of the endothelin receptor antagonist atrasentan in patients with type 2 diabetes and chronic kidney disease. [PDF]

Cardiovasc Diabetol, 2023
Smeijer JD, Kohan DE, Rossing P, Correa-Rotter R, Liew A, Tang SCW, de Zeeuw D, Gansevoort RT, Ju W, Lambers Heerspink HJ.   +9 more
europepmc   +1 more source