Results 291 to 300 of about 2,437,403 (392)

Maximizing the Therapeutic Effect of Endothelin Receptor Antagonists in Pulmonary Fibrosis: A Paradigm for Treating the Disease. [PDF]

Int J Mol Sci
Cantor J.
europepmc   +1 more source

Endothelin receptor expression in idiopathic pulmonary arterial hypertension: effect of bosentan and epoprostenol treatment

European Respiratory Journal, 2011
Susan M. Hall, Neil Davie, Nigel Klein, Sheila G. Haworth   +3 more
semanticscholar   +1 more source

Current Status of Research on Losartan in Tumour Therapy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Losartan, a widely prescribed antihypertensive agent, has attracted growing interest as a potential adjuvant in cancer therapy due to its affordability, established safety profile and pleiotropic effects. Emerging preclinical evidence demonstrates that losartan can effectively modulate the tumour microenvironment (TME) by inhibiting ...
Han Wang, Shuang Yuan, Hongjing Wang
wiley   +1 more source

Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist.

Arthritis & Rheumatism, 2004
J. Korn, M. Mayes, M. Cerinic, M. Rainisio, J. Pope, E. Hachulla, É. Rich, P. Carpentier, J. Molitor, J. Seibold, V. Hsu, L. Guillevin, Sharmila Chatterjee, H. Peter, J. Coppock, A. Herrick, P. Merkel, R. Simms, C. Denton, D. Furst, N. Nguyen, M. Gaitonde, C. Black   +22 more
semanticscholar   +1 more source

Spatial Transcriptomic Assessments of Gene Expression Profiles in Human Peri‐Implant Lesions

Journal of Clinical Periodontology, Volume 53, Issue 1, Page 137-151, January 2026.
ABSTRACT Aim To analyse gene expression profiles in human tissue samples obtained from dental implant sites with or without peri‐implantitis. Materials and Methods Soft‐tissue biopsy samples obtained from patients presenting with implants with severe peri‐implantitis and adjacent reference implants with no signs of peri‐implantitis were analysed by ...
C. Dionigi, A. C. Ericson, A. Shikhan, L. Larsson, T. Berglundh   +4 more
wiley   +1 more source

Endothelin receptor antagonism improves glucose tolerance and adipose tissue inflammation in an experimental model of systemic lupus erythematosus.

Am J Physiol Endocrinol Metab, 2023
Rivera-Gonzalez O, Case CT, Wilson NA, Speed JS, Taylor EB.   +4 more
europepmc   +1 more source

Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology

Journal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao, Rui Luo, Ying Deng, Hongqiu Yang, Yu Du   +4 more
wiley   +1 more source

Aldosterone Inactivates the Endothelin-B Receptor via a Cysteinyl Thiol Redox Switch to Decrease Pulmonary Endothelial Nitric Oxide Levels and Modulate Pulmonary Arterial Hypertension

Circulation, 2012
B. Maron, Ying‐yi Zhang, Kevin P. White, S. Y. Chan, D. Handy, Christopher E. Mahoney, J. Loscalzo, J. Leopold   +7 more
semanticscholar   +1 more source

Acute Rejection With DSA‐Negative Severe Microvascular Inflammation in a Kidney Transplant Recipient With an Isolated DPB1*04‐Mismatch Successfully Stabilised With Daratumumab

HLA, Volume 107, Issue 1, January 2026.
ABSTRACT Microvascular inflammation (MVI) in kidney allografts in the absence of detectable donor‐specific anti‐HLA antibodies (DSA) is increasingly recognised as a cause of premature graft failure following kidney transplantation. Potential mechanisms include NK cell alloreactivity mediated by recognition of mismatched HLA class I molecules (missing ...
Laura Knödl, Maike Büttner‐Herold, Markus Götz, Markus Luber, Bernd Spriewald, Michael Oellerich, Julia Beck, Bernhard Banas, Daniel Zecher   +8 more
wiley   +1 more source

Endothelin receptor B-deficient mice are protected from high-fat diet-induced metabolic syndrome. [PDF]

Mol Metab
Feger M, Meier L, Strotmann J, Hoene M, Vogt J, Wisser A, Hirschle S, Kheim MJ, Hocher B, Weigert C, Föller M.   +10 more
europepmc   +1 more source