Results 191 to 200 of about 215,964 (304)

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment. [PDF]

Nanomaterials (Basel)
Lei P, Zegeye FD, Alswady-Hoff M, Marcolungo C, Danielsen PH, Madsen AM, Wallin H, Vogel U, Zienolddiny-Narui S, Erdem JS.   +9 more
europepmc   +1 more source

Acute Inhalation Exposure to Ultrafine Carbon Black Alters Mitochondrial Substrate Utilization in the Heart

Environmental Toxicology, EarlyView.
ABSTRACT A majority of deaths associated with air pollution are attributed to cardiovascular and heart diseases. Carbon black that represents the carbon core of particulate matter, a major component of air pollution, has been shown to result in cardiac mitochondrial dysfunction.
William E. Mullen, Jackson E. Stewart, Rahatul Islam, Salik Hussain, Dharendra Thapa   +4 more
wiley   +1 more source

Modulation of LPS-associated virulence activity for reduction of periodontal inflammatory burden. [PDF]

Front Microbiol
Dong A, Lehto M, Putaala J, Paju S, Pussinen P, Zaric S.   +5 more
europepmc   +1 more source

Variability in German cockroach extract composition greatly impacts T cell potency in cockroach-allergic donors [PDF]

, 2019
Bacharier, Leonard B, Beigelman, Avraham, et al,   +2 more
core   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Ex vivo allergen specific type 2 immune responses in house dust mite-driven acute airway inflammation in mice depend on allergen extract characteristics. [PDF]

Respir Res
Verstegen REM, Thijssen S, Kostadinova AI, Garssen J, Folkerts G, Hendriks RW, Willemsen LEM.   +6 more
europepmc   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Endotoxin Pretreatment Mitigates Myocardial Ischemia-Reperfusion Injury Through Preservation of Mitochondrial Respiration: A Combined Assessment of In Vivo, Ex Vivo, and In Vitro Data. [PDF]

Int J Mol Sci
Habimana R, Seong J, Jo Y, Kim RH, Kim HJ, Choi KS, Kayumov M, Obiweluozor FO, Kim WI, Cho HJ, Kim D, Na KJ, Jeong I.   +12 more
europepmc   +1 more source

Allochthonous chemical cues drive predation by a top carnivore

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Identifying the mechanisms by which mobile predators detect and select prey remains a central challenge in sensory biology and functional ecology. This study provides the first direct evidence that chemical cues associated with allochthonous organic matter (e.g.
Ryan P. Ferrer, Richard K. Zimmer
wiley   +1 more source