Results 91 to 100 of about 231,977 (312)

Endovascular Drug Delivery

Life
Drug-eluting stents (DES) and balloons revolutionize atherosclerosis treatment by targeting hyperplastic tissue responses through effective local drug delivery strategies. This review examines approved and emerging endovascular devices, discussing drug release mechanisms and their impacts on arterial drug distribution. It emphasizes the crucial role of
Claudiu N. Lungu, Andreea Creteanu, Mihaela C. Mehedinti   +2 more
openaire   +3 more sources

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Data science of stroke imaging and enlightenment of the penumbra. [PDF]

, 2015
Imaging protocols of acute ischemic stroke continue to hold significant uncertainties regarding patient selection for reperfusion therapy with thrombolysis and mechanical thrombectomy.
Liebeskind, David S, Nour, May, Scalzo, Fabien   +2 more
core   +2 more sources

Endovascular Thrombectomy [PDF]

Stroke, 2018
Background and Purpose— This study aimed to explore safety of tirofiban in endovascular treatment of acute ischemic stroke. Methods— Two hundred eighteen ischemic stroke patients receiving endovascular ...
Wu, Yuefei, Yin, Congguo, Yang, Jianhong, Jiang, Lin, Parsons, Mark W., Lin, Longting   +5 more
openaire   +1 more source

Functional Outcomes at 90 Days in Octogenarians Undergoing Thrombectomy for Acute Ischemic Stroke: A Prospective Cohort Study and Meta-Analysis

Frontiers in Neurology, 2019
Background: Elderly patients account for 30% of acute ischemic stroke (AIS) but are under-represented in randomized controlled trials of endovascular thrombectomy (EVT). Meta-analysis of “real world” studies evaluating 90-day outcomes in elderly patients
Angelos Sharobeam, Dennis John Cordato, Dennis John Cordato, Dennis John Cordato, Nathan Manning, Nathan Manning, Nathan Manning, Nathan Manning, Andrew Cheung, Andrew Cheung, Jason Wenderoth, Jason Wenderoth, Jason Wenderoth, Cecilia Cappelen-Smith, Cecilia Cappelen-Smith, Cecilia Cappelen-Smith   +15 more
doaj   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Timing of vessel imaging for suspected large vessel occlusions does not affect groin puncture time in transfer patients with stroke. [PDF]

, 2018
BACKGROUND: Access to endovascular therapy (ET) in cases of acute ischemic stroke may be limited, and rapid transfer of eligible patients to hospitals with endovascular capability is needed.
Dhamoon, Mandip S., Fifi, Johanna T., Liang, John W., Stein, Laura, Tuhrim, Stanley, Wilson, Natalie   +5 more
core   +1 more source

Are you suffering from a large arterial occlusion? Please raise your arm! [PDF]

, 2018
Background and purpose: Triage tools to identify candidates for thrombectomy are of utmost importance in acute stroke. No prognostic tool has yet gained any widespread use.
Abdul-Rahim, Azmil H., Ahmed, Niaz, Bottai, Matteo, Cooray, Charith, Krajina, Antonin, Mazya, Michael V., Mikulik, Robert, Moreira, Tiago Prazeres, Nevsimalova, Miroslava, Scheitz, Jan F., Toni, Danilo, Wahlgren, Nils   +11 more
core   +1 more source

Case report of successful treatment of patient with ruptured celiac artery aneurysm

Frontiers in Surgery
Celiac artery aneurysms (САА) represent the fourth most common visceral artery aneurysm. Despite its rarity, CAA carries a definite risk of rupture and/or other serious complications, which can be fatal. The reported rupture risk varies in the scientific
I. A. Semenenko, I. A. Semenenko, V. A. Yumasheva, N. Alieva, N. V. Yasnopolskaya, V. M. Sysoev   +5 more
doaj   +1 more source

Intra-arterial tirofiban in a male nonagenarian with acute ischemic stroke: A case report

Open Life Sciences, 2019
Nonagenarians with acute ischemic stroke tend to have a higher mortality and morbidity than younger patients. Tirofiban is a glycoprotein IIb/IIIa antagonist that has a therapeutic potential for ischemic stroke.
Ding Xianhui, Gu Ao, Yang Qian, Zhou Zhiming, Shi Xiaolei   +4 more
doaj   +1 more source