Results 221 to 230 of about 2,683,923 (303)

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou   +9 more
wiley   +1 more source

Effects of Danhong Injection on 90‐Day Functional Outcome in Acute Ischemic Stroke: An Adaptive, Multicenter, Randomized, Double‐Blind, Placebo‐Controlled Phase IV Trial

open access: yesMedComm, Volume 7, Issue 11, November 2026.
In a randomized trial of 1505 thrombolysis‐ineligible AIS patients, 14‐day Danhong injection improved neurological recovery, raising mRS ≤1 rate by 5.33% versus placebo. RNA sequencing of 39 patients identified 19 DEMs, including the paired targeted modules HBG2/TMEM108, whose time‐dependent joint association with outcome (−0.729 to 1) was described ...
Jun Liu   +21 more
wiley   +1 more source

Geometry‐Related Technical Complications After LVAD Implantation: Impact on Device Dysfunction and Clinical Outcomes

open access: yesArtificial Organs, Volume 50, Issue 11, Page 1605-1615, November 2026.
Preventable geometric failure modes, such as outflow graft kinking and inflow malposition, frequently cause HeartMate 3 dysfunction. This study identifies these complications as key drivers of device‐related morbidity, highlighting the importance of optimized surgical positioning to ensure long‐term device performance and improved clinical outcomes ...
Ali Saad Merzah   +17 more
wiley   +1 more source

SURGELLA: A Scoping Review of Impella‐Assisted Hemodynamic Support in High‐Risk Non‐Cardiac Surgery

open access: yesArtificial Organs, Volume 50, Issue 11, Page 1532-1545, November 2026.
In selected patients with severe LV dysfunction, Impella‐supported non‐cardiac surgery may provide a temporary hemodynamic bridge to otherwise prohibitive procedures. Published evidence remains limited to a small number of highly selected cases, supporting technical feasibility rather than comparative benefit or generalizable safety.
Hussein Elghazaly   +6 more
wiley   +1 more source

Serum IL-6 and functional outcome after endovascular therapy: the mediating role of infarct volume growth in acute ischemic stroke. [PDF]

open access: yesFront Immunol
Li S   +12 more
europepmc   +1 more source

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

open access: yesArtificial Organs, Volume 50, Issue 11, Page 1657-1667, November 2026.
In this series of 19 DCD donors using TA‐NRP, 89.5% of hearts were successfully transplanted with no PGD, no postoperative ECMO, and no 30‐day mortality, demonstrating the feasibility and safety of this approach. ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged ...
Maria Benedetto   +11 more
wiley   +1 more source

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