Results 261 to 270 of about 4,744,541 (408)
CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed +22 morewiley +1 more sourceMachine learning methods for predicting adverse drug events: A systematic review
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 422-444, February 2026.Abstract
Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda +8 morewiley +1 more sourceEndovascular Versus Medical Therapy in Posterior Cerebral Artery Stroke: Role of Baseline NIHSS Score and Occlusion Site
Davide Strambo, Patrik Michel, Thanh N. Nguyen, Mohamad Abdalkader, Muhammad M. Qureshi, Daniel Strbian, Christian Herweh, Markus Möhlenbruch, Silja Räty, Marta Olivé‐Gadea, Marc Ribó, Marios Psychogios, Urs Fischer, Anh Nguyên, Joji B. Kuramatsu, David Haupenthal, Martin Köhrmann, Cornelius Deuschl, Jordi Kühne Escolà, Jelle Demeestere, Robin Lemmens, Lieselotte Vandewalle, Shadi Yaghi, Liqi Shu, Volker Puetz, Daniel Kaiser, Johannes Kaesmacher, Adnan Mujanović, Dominique Cornelius Marterstock, Tobias Engelhorn, Manuel Requena, Hormuzdiyar H. Dasenbrock, Piers Klein, Diogo C Haussen, Mahmoud Mohammaden, Hend Abdelhamid, Lorena Souza Viana, Bruno Cunha, Isabel Fragata, Michele Romoli, Francesco Diana, Wei Hu, Chao Zhang, Pekka Virtanen, Riikka Lauha, Jessica Jesser, Judith Clark, Stavros Matsoukas, Johanna T Fifi, Sunil A. Sheth, Sergio Salazar‐Marioni, João Pedro Marto, João Nuno Ramos, Milena Miszczuk, Christoph Riegler, Sven Poli, Khouloud Poli, Ashutosh P. Jadhav, Shashvat M. Desai, Volker Maus, Maximilian Kaeder, Adnan H. Siddiqui, André Monteiro, Hesham Masoud, Neil Suryadareva, Maxim Mokin, Shail Thanki, Kemal Alpay, Pauli Ylikotila, James E. Siegler, Italo Linfante, Guilherme Dabus, Negar Asdaghi, Vasu Saini, Christian H. Nolte, Eberhard Siebert, Bettina L. Serrallach, Charlotte S. Weyland, Uta Hanning, Lukas Meyer, Anne Berberich, Peter Ringleb, Raul G. Nogueira, Simon Nagel +83 moreopenalex +1 more sourceThe Correlations of Clinical Outcomes and Vascular Morphology With Infarct Patterns in Middle Cerebral Arterial Occlusion
Brain and Behavior, Volume 16, Issue 2, February 2026.For stroke caused by large vessel occlusion in M1 segment of middle cerebral artery (MCA), a tortuous and long M1 segment of contralateral MCA (cMCA) correlates with the onset of borderzone infarct. In those with a less tortuous cMCA‐M1 segment, a thin and short M1 segment correlates with large infarct.ZhiRong Cai, Yuan Chen, ShaoQing Pei, Yue He, YaNan Zhu, Rui Zhang, JingWei Lin, Yi Yang, Ying Zhu +8 morewiley +1 more sourceDirect thrombectomy versus bridging alteplase medicine in anterior circulation stroke following endovascular therapy: a multi-center cohort study. [PDF]
Eur J Med ResZeng X, Feng M, Mofatteh M, Chen L, Yi J, Xu Z, Yan Z, Ma J, Zhou S, Wang H, Lin X, Lai Y, Peng W, Zhou M, Yang S. +14 moreeuropepmc +1 more source