Results 41 to 50 of about 11,658 (266)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Review on Thermal Behavior and Cooling Aspects of Axial Flux Permanent Magnet Motors–A Mechanical Approach

open access: yesIEEE Access, 2023
With the increasing demand for high-energy density motors for applications such as electric vehicles and aircraft propulsion, axial flux permanent magnet motors are promising.
Rahul Roy   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Assessing the impact of three‐phase rewinding of a failed single‐phase motor on efficiency improvement and energy saving

open access: yesIET Electric Power Applications, 2023
Induction motors, particularly single‐phase induction motors (SPIMs), represent the major consumption of power in the household sector. SPIMs that fail during their life cycle represent the best opportunity to improve their efficiency by replacing or ...
Hamidreza Akbari Resketi   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Design of a High-Specific-Power Traction Motor: Innovations and Strategies for Superior Performance

open access: yesIEEE Access
In electric vehicle (EV) traction, energy conversion by electric motors must be material and energy efficient to reduce environmental burden caused by the manufacture and operation of the systems and to help in efficient transition towards net zero ...
Juha J. Pyrhonen   +14 more
doaj   +1 more source

Electric generators and motors: An overview

open access: yesCES Transactions on Electrical Machines and Systems, 2017
Starting with Faraday's law of electromagnetic induction in 1831, electric (electromagnetic) machines have been developed ever since as “assembles” of electric and magnetic coupled circuits that convert mechanical to electrical energy (in generators) and
Ion Boldea
doaj   +1 more source

48-Volt Energy Efficient Domestic Appliances With Flux Switching Motor Drive System–Design, Simulation, and Comparison

open access: yesIEEE Access, 2022
Energy-Efficient domestic appliances are the need of the hour. This paper explores the importance of 48-Volt domestic appliances especially those operated with an electric motor drive system.
Natesan Chokkalingam Lenin
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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