Results 41 to 50 of about 11,658 (266)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
With the increasing demand for high-energy density motors for applications such as electric vehicles and aircraft propulsion, axial flux permanent magnet motors are promising.
Rahul Roy +2 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Induction motors, particularly single‐phase induction motors (SPIMs), represent the major consumption of power in the household sector. SPIMs that fail during their life cycle represent the best opportunity to improve their efficiency by replacing or ...
Hamidreza Akbari Resketi +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Design of a High-Specific-Power Traction Motor: Innovations and Strategies for Superior Performance
In electric vehicle (EV) traction, energy conversion by electric motors must be material and energy efficient to reduce environmental burden caused by the manufacture and operation of the systems and to help in efficient transition towards net zero ...
Juha J. Pyrhonen +14 more
doaj +1 more source
Electric generators and motors: An overview
Starting with Faraday's law of electromagnetic induction in 1831, electric (electromagnetic) machines have been developed ever since as “assembles” of electric and magnetic coupled circuits that convert mechanical to electrical energy (in generators) and
Ion Boldea
doaj +1 more source
Energy-Efficient domestic appliances are the need of the hour. This paper explores the importance of 48-Volt domestic appliances especially those operated with an electric motor drive system.
Natesan Chokkalingam Lenin
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

