Results 91 to 100 of about 7,102,101 (318)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Retracted: Legal Path of Rural Revitalization for Decision-Making Risk Prevention of Internet of Things Algorithm

International Transactions on Electrical Energy Systems, 2023
International Transactions on Electrical Energy Systems
doaj   +1 more source

Energy-Smart Building Choices: How Parents and Teachers Are Helping to Create Better Environments for Learning

, 2001
Most K-12 schools could save 25% of their energy costs by being smart about energy. Nationwide, the savings potential is $6 billion. While improving energy use in buildings and busses, schools are likely to create better places for teaching and learning,
Team, Energy Smart Schools
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Retracted: Visual Planarization in Oil Painting Techniques in Digital Information Age

International Transactions on Electrical Energy Systems, 2023
International Transactions on Electrical Energy Systems
doaj   +1 more source

Business and industry e, energy, resources

, 2005
Title from p. [1] of PDF (viewed Mar. 13, 2006).; "Created: 9/7/2005...; Modified 9/21/2005"--Document properties screen.; Designed to be printed on one sheet, front and back, and then folded into a pamphlet.; Harvested from the web on 3/14/06Lists low ...
Ohio. Office of Energy Efficiency.
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Retracted: Teaching Practice of College Students’ Marketing Course Based on the Background of the Internet Era

International Transactions on Electrical Energy Systems, 2023
International Transactions on Electrical Energy Systems
doaj   +1 more source

Addendum to A Blueprint for Ocean Energy Development 2010-2015

OWET convened the second annual OWET Developersʼ Summit on August 2, 2011 in Portland, Oregon. The Summit brought together participants, both new and those who had attended the first OWET Developersʼ Summit 2010, to review the Blueprint for Ocean Energy ...
Oregon Wave Energy Trust
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source