Results 41 to 50 of about 13,354,697 (314)

Front Cover [PDF]

, 2015
Clockwise from top left: Michael Lindblad ’94, Nathaniel Wight ’99, Tim Love ...
Mileham, Mardi, Zayed Future Energy Prize   +1 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Sustainable energy for whom? Governing pro-poor, low-carbon pathways to development: lessons from solar PV in Kenya [PDF]

, 2014
Using a combination of insights from innovation studies, sociotechnical transitions theory and the STEPS pathways approach, this paper analyses the evolution of the Kenyan photovoltaics (PV) market. Considered by many to be an exemplar of private sector
Becker, Sarah, Byrne, Robert, Ely, Adrian, Gollwitzer, Lorenz, Kirumba, Edith, Ockwell, David, Ozor, Nicholas, Urama, Kevin   +7 more
core  

Energy-efficient street lighting through embedded adaptive intelligence [PDF]

, 2013
Streetlights place a heavy demand on electricity usage, providing significant financial and environmental burdens. Consequently, initiatives to reduce energy consumption have been proposed, usually by turning off or dimming the streetlight. In this paper,
Lau, Sei Ping, Merrett, Geoff V., White, Neil M.   +2 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Neutron time-of-flight measurements of charged-particle energy loss in inertial confinement fusion plasmas [PDF]

, 2019
Neutron spectra from secondary ^{3}H(d,n)α reactions produced by an implosion of a deuterium-gas capsule at the National Ignition Facility have been measured with order-of-magnitude improvements in statistics and resolution over past experiments.
Caggiano, J. A., Cerjan, C. J., Divol, L., Eckart, M. J., Gericke, Dirk O., Graziani, F. R., Grim, G. P., Hansen, S. B, Hartouni, E. P, Hatarik, R., Hatchett, S. P., Hayes, A. K., Hopkins, L. F. Berzak, Johnson, M. Gatu, Khan, S. F., Knauer, J. P., Le Pape, S., MacKinnon, A. J., McNaney, J. M., Meezan, N. B., Rinderknecht, H. G., Sayre, D. B., Schneider, D. H., Sepke, S. M., Shaughnessy, D. A., Stoeffl, W., Yeamans, C. B., Zylstra, A. B.   +27 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

UK energy strategies under uncertainty: synthesis report [PDF]

, 2014
No description ...
Gross, Rob, Ketsopoulou, Ioanna, Watson, Jim, Winskel, Mark   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source