Results 91 to 100 of about 4,429,470 (297)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Investigating the Impacts of Energy Access Scenarios in the Nigerian Household Sector by 2030

Resources, 2019
Lack of access to modern forms of energy continues to hamper socio-economic development in Nigeria, and about 94% and 39% of the Nigerian population do not have access to clean cooking equipment and electricity, respectively.
Michael O. Dioha, Nnaemeka Vincent Emodi   +1 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Accelerating access to energy services: Way forward

Advances in Climate Change Research, 2017
As nearly a fifth of the world's population still lives without access to electricity and double that number with no access to modern cooking technologies, both public and private sector players have invested resources in developing infrastructure to address this energy gap.
Rehman, Ibrahim Hafeezur, Sreekumar, Arun, Gill, Bigsna, Worrell, Ernst   +3 more
openaire   +4 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Robust Transmissions in Wireless Powered Multi-Relay Networks with Chance Interference Constraints

, 2018
In this paper, we consider a wireless powered multi-relay network in which a multi-antenna hybrid access point underlaying a cellular system transmits information to distant receivers.
Cheng, Wenqing, Gao, Lin, Gong, Shimin, Niyato, Dusit, Xu, Jing, Zou, Yuze   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Neural Network‐Based Multiple‐Model Adaptive Control of Grid‐Connected Inverters in Weak Grids

IET Power Electronics
Grid‐connected inverters (GCIs) operating in grid‐following (GFL) control may suffer from instability when connected to a weak grid characterised by a low short‐circuit ratio (SCR). Conversely, GCIs operating in grid‐forming (GFM) control may be unstable
Yu Xiao, Xing Zhang, Feng Han
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source