Results 121 to 130 of about 4,429,470 (297)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Measuring Energy Poverty: Focusing on What Matters [PDF]

open access: yes
The provision of modern energy services is recognised as a critical foundation for sustainable development, and is central to the everyday lives of people.
Patrick Nussbaumer, Morgan Bazilian, Vijay Modi and Kandeh K. Yumkella
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Increasing electricity access for health facilities in Ghana through solar powered mini-grids—a GIS-based energy system modelling approach

open access: yesEnvironmental Research: Infrastructure and Sustainability
The research aims to identify which healthcare facilities (HCFs) in Ghana are suitable for electrification using photovoltaic mini-grids to increase their energy self-sufficiency and reliability of services provided.
Katrin Lammers   +3 more
doaj   +1 more source

Progressing Sustainable Development Goal 7 via Energy Access: Results from the 27 EU Member States

open access: yesEnergies
Energy plays an undeniable role in socioeconomic development. The energy issue is addressed in Agenda 2030 as one of its 17 goals. The article presents research on the statistical evaluation of the level of implementation of Sustainable Development Goal ...
Barbara Fura, Elżbieta Skrzypek
doaj   +1 more source

Home - About - Disclaimer - Privacy