Results 121 to 130 of about 6,219,573 (312)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
High-resolution electron energy analyzer with wide acceptance angle for hard X-ray photoelectron holography: integrating PESCATORA and retarding field analyzer [PDF]
Photoelectron holography requires measuring the photoelectron angular distribution across a wide acceptance angle, typically exceeding ±45°. This necessitates an electron analyzer that offers both a large acceptance angle and high energy resolution for ...
Hashimoto, Yusuke +8 more
core +2 more sources
Statistical Properties of Molecular Ions in the Ring Current Observed by the Arase (ERG) Satellite
Geophysical Research Letters, 2019 Molecular ions in the magnetosphere can be a tracer of fast ion outflows from the deep ionosphere. Statistical properties of molecular ions (O2+/NO+/N2+) in the ring current are investigated based on ion composition measurements (
K. Seki +12 more
doaj +1 more source
This research examines intraday electricity price volatility in the Great Britain energy market over a specific period. Using quantitative data analysis, it identifies key trends, price fluctuations, and market dynamics that influence electricity trading.
openaire +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Time-of-flight SIMS/MSRI reflectron mass analyzer and method [PDF]
, 1997 A method and apparatus for analyzing the surface characteristics of a sample by Secondary Ion Mass Spectroscopy (SIMS) and Mass Spectroscopy of Recoiled Ions (MSFU) is provided.
Holecek, John C. +4 more
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