Results 171 to 180 of about 1,262,608 (310)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Protecting women's health in sport: the role of low energy availability in the Female Athlete Triad and RED-S. [PDF]

Front Sports Act Living
Ghazzawi HA, Khataybeh B, Al Aqaili R, Alnimer L, Omoush RM, Ali HA.   +5 more
europepmc   +1 more source

Measurements of the Wind Energy Resource in the Latvia

In the Baltic countries interest to the renewable energy is growing. Government support and availability of large unpopulated areas on the coast makes attractive use of these lands for the placement of large wind power plants (WPP).
Šipkovs, Pēteris, Pugačevs, Vladislavs, Bezrukovs, Vladimirs, Silutins, V., Bezrukov, Valerijs   +4 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

SWEET1-mediated glucose transport is crucial for energy availability in Arabidopsis. [PDF]

New Phytol
Xue X, Li J, Yu YC, Chen LQ.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Availability of direct normal radiation for solar furnace processing: A case study

, 1994
Predicting the availability of direct normal solar radiation is important for scheduling tests and estimating economics of solar furnaces. This paper looks at historical hourly average direct normal data to predict seasonal trends and report historical ...
Bingham, C. E.
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Energy availability outperforms topographic heterogeneity in predicting global patterns of mountain endemic plant richness. [PDF]

iScience
Gu Y, Ji J, Li Z, Jiang Z, Sun W.
europepmc   +1 more source