Results 61 to 70 of about 1,262,608 (310)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
MetabolitesRelative energy deficiency in sport (RED-S) is a condition that arises from persistent low energy availability (LEA), which affects the hypothalamic–pituitary axis and results in alterations of several hormones in both male and female athletes.
Chiara Tuma +3 more
doaj +1 more source
, 2022 Utilizing solar energy for heat supply can reduce CO2 emissions and mitigate global climate change. In the Nordic region (e.g., Iceland and Finland), a tremendous seasonal mismatch exists between the availability of solar radiation and building heating ...
Hirvonen, Janne +6 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
MetabolitesActive athletes frequently develop low energy (LEA) and protein availabilities (LPA) with consequent changes in the vital metabolic processes, especially resting metabolic rate (RMR) and substrate utilization.
Mahmoud M. A. Abulmeaty +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Journal of the Atmospheric Sciences, 2012 Abstract The total potential energy of the atmosphere is the sum of its internal and gravitational energies. The portion of this total energy available to be converted into kinetic energy is determined relative to an isothermal, hydrostatic, equilibrium atmosphere that is convectively and dynamically “dead.” The temperature of this ...
openaire +1 more source
, 2012 This paper is the last in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.This report reviews the future availability of uranium resources via an assessment of the demand for uranium from ...
Future Energy Solutions, AEA Technology plc
core
, 2012 This is the Pre-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 Maney PublishingBackground: The use of electrophysical agents has a historically important role in physiotherapy practice.
Farrow, A, Shah, SGS
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source