Results 81 to 90 of about 465,658 (261)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Optimal Sizing of Fuel Cell and Battery in a Direct-Hybrid for Electric Aircraft

Aerospace
The climate impact of aviation can be reduced using powertrains based on hydrogen fuel cells and batteries. Combining both technologies in a direct-hybrid without a DC/DC converter is a promising approach for light-weight systems.
Tobias Graf, Robin Fonk, Christiane Bauer, Josef Kallo, Caroline Willich   +4 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

CALiSol-23: Experimental electrolyte conductivity data for various Li-salts and solvent combinations

Scientific Data
Ion transport in non-aqueous electrolytes is crucial for high performance lithium-ion battery (LIB) development. The design of superior electrolytes requires extensive experimentation across the compositional space.
Paolo de Blasio, Jonas Elsborg, Tejs Vegge, Eibar Flores, Arghya Bhowmik   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Tri-Axial Shear Tests on Hydrate-Bearing Sediments during Hydrate Dissociation with Depressurization

Energies, 2018
A series of tri-axial shear tests were carried out to determine the stress and strain characteristics, as well as the volume deformation of methane hydrate-bearing sediments during gas hydrate dissociation.
Dongliang Li, Qi Wu, Zhe Wang, Jingsheng Lu, Deqing Liang, Xiaosen Li   +5 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Model-Based Analysis of Transient Currents to Dimension a Vehicular Power System With Electronic Fuses Regarding Short Circuit Selectivity

IEEE Open Journal of Vehicular Technology
A fail-operational vehicular power system requires the selective tripping of electronic fuses (eFuses) in case of a fault event, e.g. short circuit, impermissible wire temperature.
Christoph Mayer, Martin Baumann, Luis Finkl, Leo T. Peters, Hans-Georg Herzog   +4 more
doaj   +1 more source

Anti-Agglomerator of Tetra-n-Butyl Ammonium Bromide Hydrate and Its Effect on Hydrate-Based CO2 Capture

Energies, 2018
Tetra-n-butyl ammonium bromide (TBAB) was widely used in the research fields of cold storage and CO2 hydrate separation due to its high phase change latent heat and thermodynamic promotion for hydrate formation.
Rong Li, Xiao-Sen Li, Zhao-Yang Chen, Yu Zhang, Chun-Gang Xu, Zhi-Ming Xia   +5 more
doaj   +1 more source