Results 81 to 90 of about 6,988,656 (258)

Modelling of erosion-corrosion processes in energy conversion systems : summary report

, 1991
Summary report describing the modelling of erosion-corrosion processes in energy conversion ...
Stephenson, D., Nicholls, J.R., Debruyen, W., Stack, Margaret, Casteels, F., Norton, J.F., Prescott, R., Englen, W., Polden, M., Wouters, G., Stott, F.H., Gandry, M.   +11 more
core   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A state-of-the-art review on dual purpose seaweeds utilization for wastewater treatment and crude bio-oil production

, 2020
Due to the negative environmental impacts of fossil fuels and the increasing global energy demands, biofuels are receiving increasing attention as the best short-term substitute for petroleum.
Zhao, Shuang, Uzoejinwa, Benjamin Bernard, Huang, Jin, Wang, Qingyuan, Zheng, Anqing, Wang, Shuang, Abomohra, Abd El-Fatah   +6 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Advanced Energy Conversion

, 1976
The potential for advanced energy conversion techniques with high temperature efficiency and/or lower energy conversion costs for coal-fired and nuclear power plants is discussed. Advanced energy conversion developments in open combined cycle gas turbine,
Berg, Daniel, Somers, Edward, Fickett, Arnold   +2 more
core   +3 more sources

99.7% Efficient 800 V ZVS Partial Power Switched Capacitor Buck Converter With 650 V GaN HEMTs

IEEE Open Journal of Power Electronics
This letter presents a highly efficient synchronous buck converter based on a partial power processing switched capacitor topology with two 650 V gallium nitride (GaN) transistors and a diode-based resonant circuit.
Veeramanikandan Murugesan, Ole Bauer, Adrian Sollner, Ines Bennour, Nejila Parspour, Stefan Monch   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Unifying the ORR and OER with surface oxygen and extracting their intrinsic activities on platinum

Nature Communications
Common half-cell measurements deliver oxygen reduction activities linked to the chosen scan rate, limiting their value for fundamental and comparative studies on platinum.
Benedikt Axel Brandes, Yogeshwaran Krishnan, Fabian Luca Buchauer, Heine Anton Hansen, Johan Hjelm   +4 more
doaj   +1 more source