Results 81 to 90 of about 9,361,493 (309)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Shaping array design of marine current energy converters through scaled experimental analysis [PDF]

, 2013
Marine current energy converters or tidal turbines represent an emerging renewable energy technology that can provide a predictable supply of electricity.
Myers, L.E., Bahaj, A.S., Myers, L. E., Bahaj, AbuBakr S.,   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Papel de las bajas emisiones de carbono H2 en la transición energética de Colombia: Evaluación ambiental de las vías de producción de H2 para un esquema de certificación

, 2022
15 páginasHydrogen (H2) is a low-carbon carrier. Hence, measuring the impact of its supply chain is key to guaranteeing environmental benefits. This research proposes a classification of H2 in Colombia based on its carbon footprint and source.
Cobo, Martha, Barraza Botet, Cesar, Moreno, Juan, Sanchez, Nestor   +3 more
core   +1 more source

Bifacial Thermophotovoltaic Energy Conversion

ACS Photonics, 2023
Thermophotovoltaic (TPV) energy conversion efficiency has recently surpassed 30%. The key behind such high efficiency is the inclusion of a highly efficient mirror in the rear of the TPV cell that turns back to the thermal emitter the outband energy photons.
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Characterization of a rotary piezoelectric energy harvester based on plucking excitation for knee-joint wearable applications [PDF]

, 2012
Wearable medical and electronic devices demand a similarly wearable electrical power supply. Human-based piezoelectric energy harvesters may be the solution, but the mismatch between the typical frequencies of human activities and the optimal operating ...
Pozzi, Michele, Zhu, Meiling
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Effects of environmental factors on the conversion efficiency of solar thermoelectric co-generators comprising parabola trough collectors and thermoelectric modules without evacuated tubular collector

, 2014
Solar thermoelectric co-generators (STECGs) are an attractive means of supplying electric power and heat simultaneously and economically. Here we examine the effects of environmental factors on the conversion efficiencies of a new type of STECG ...
Miao, Lei, Shen, Yang, Fisher, C. A. J., Ohno, Kaoru, Lin, Hong, Zhou, Jianhua, Kang, Yi Pu, Li, Chao, Zhang, Ming   +8 more
core   +1 more source