Results 41 to 50 of about 188,981 (310)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Dielectric elastomer generator with diaphragm configuration
The dielectric elastomer generator (VHB 4905, 3M) with diaphragm configuration was investigated with the constant-voltage harvesting scheme in order to investigate its energy harvesting ability. The maximum energy density and energy conversion efficiency
Song Zhen-Qiang+4 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Multimode luminescent materials exhibit tunable photon emissions under different excitation or stimuli channels, endowing them high encoding capacity and confidentiality for anti‐counterfeiting and encryption.
Bingyin Kong+9 more
doaj +1 more source
Dye-sensitized solar cells (DSSCs) were fabricated using open-ended freestanding TiO2 nanotube arrays functionalized with Ag nanoparticles (NPs) in the channel to create a plasmonic effect, and then coated with large TiO2 NPs to create a scattering ...
Won-Yeop Rho+5 more
doaj +1 more source
Kinetic Energy Distribution of Water Droplets in Fixed Solar Sprinkler Irrigation System
【Background】 Solar sprinkler irrigation system is energy-efficient and can reduce operation costs, but it is susceptible to weather and timing of irrigation as insufficient energy supply may occur when demand for power peaks during the irrigation.
LIU Junping+4 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Energy conversion efficiency in human left ventricle. [PDF]
BACKGROUND Left ventricular mechanical efficiency is one of the most important measures of left ventricular pump performance. Several clinical studies, however, have shown that mechanical efficiency does not fall substantially as the heart fails.
Shigetake Sasayama+5 more
openaire +3 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Global energy security relies on fossil-based resources that are affiliated with the source of global warming, apart from punches of political and economic instabilities.
Shumet Sharew+4 more
doaj +1 more source