Results 51 to 60 of about 992,076 (345)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Hysteresis Induced by Incomplete Cationic Redox in Li‐Rich 3d‐Transition‐Metal Layered Oxides Cathodes

open access: yesAdvanced Science, 2022
Activation of oxygen redox during the first cycle has been reported as the main trigger of voltage hysteresis during further cycles in high‐energy‐density Li‐rich 3d‐transition‐metal layered oxides.
Liang Fang   +11 more
doaj   +1 more source

RETRACTED: How Do Green Finance and Energy Efficiency Mitigate Carbon Emissions Without Reducing Economic Growth in G7 Countries?

open access: yesFrontiers in Psychology, 2022
Climate change is one of the most serious threats facing the world today. Environmental pollution and depletion of natural resources have been highlighted by the United Nations Sustainable Development Goals (SDGs), paving the way for modern concepts such
Zhen Fang, Can Yang, Xiaowei Song
doaj   +1 more source

Sustainability, overall and process efficiency of energy crops [PDF]

open access: yes, 2008
A method to calculate efficiency of energy crop production including sun energy, direct and indirect energy for cultivation, processing, and conversion into fuel is demonstrated using rape and derived fuels as an example.
Schäfer, Winfried
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A High-Efficiency Driver Circuit for a Gas-Sensor Microheater Based on a Switch-Mode DC-to-DC Converter

open access: yesSensors, 2020
Low power consumption is one of the critical factors for successful Internet of Things (IoT) applications. In such applications, gas sensors have become a main source of power consumption because energy conversion efficiency of the microheater is ...
Tzu-Sen Yang, Jin-Chern Chiou
doaj   +1 more source

Efficiency of Negative-Illumination Photovoltaic Energy Conversion

open access: yesACS Applied Energy Materials
Infrared diodes generate electricity from thermal radiation emitted from themselves. The negative process of photovoltaic effect has been expected for application to energy harvesting systems converting from terrestrial radiation. However, its energy conversion efficiency has been known to be very low.
Toru Matsuura   +2 more
openaire   +2 more sources

Fast and Efficient Information Transmission with Burst Spikes in Deep Spiking Neural Networks

open access: yes, 2019
The spiking neural networks (SNNs) are considered as one of the most promising artificial neural networks due to their energy efficient computing capability.
Choe, Hyeokjun   +3 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

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