Results 51 to 60 of about 362,226 (259)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Comparative Study of Multi-Step Forecasting Algorithms for Real-Time Load Profiling in Smelting Plant Electricity Demand

IEEE Access
The transition to deregulated energy markets has transformed electricity from a fixed cost into a strategic variable for power-intensive industries. Smelting plants, characterized by volatile, multi-megawatt load signatures, face acute exposure to price ...
Samrawit Bzayene Fesseha, Bin Li, Bing Qi, Songsong Chen, Feixiang Gong   +4 more
doaj   +1 more source

Membranes and the setting of energy demand [PDF]

Journal of Experimental Biology, 2005
SUMMARYIn his classic 1961 book, The Fire of Life, Max Kleiber presented a critique of the theories advanced to explain the BMR-body size relationship. One of the theories he dismissed was that the chemical composition of animals varies with body size. Since this time, however, much has been learned about the make-up of BMR in different animals as well
Hulbert, Anthony J, Else, Paul
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Energy demand in sludge dewatering [PDF]

Water Research, 2005
This work investigates the energy required to dewater a suspension, i.e., activated sludge dewatered by centrifugation or consolidation. Total energy input to the suspension from the dewatering device, bond strength between adjacent water and solid surface, and intra-cake friction loss were evaluated for original and flocculated sludges. In centrifugal
Chu, C.P., Lee, D.J., Chang, C.Y.
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Multi-time Scale Voltage-Reactive Power Control for Distribution Network with Distributed Generation

Journal of Harbin University of Science and Technology
Aiming at the problems of network loss increase, voltage deviation and voltage exceeding specified limits when large- scale distributed generations ( DGs) connected to distribution network ( DN) , this paper proposes a multi-time scale coordinated ...
LIU Haotian, ZHENG Chuyu, LENG Yang, LI Qin, ZHANG Hua, CHEN Shidu, LI Jiayong   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

GRO-Bagging Day-Ahead Power Curve Forecasting Model Based on Multi-Cycle Feature Extraction

IEEE Access
Power loads usually have multiple cycles, and the traditional forecasting methods only use the historical loads under various types of cycles together as input features to construct the forecasting model, ignoring the deep features under multiple cycles.
Yaoxian Liu, Kaixin Zhang, Songsong Chen, Ying Zhou, Jingwen Chen   +4 more
doaj   +1 more source