Results 171 to 180 of about 1,388,181 (313)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Statistical average strain energy density fatigue estimation of strut-based metamaterials via synthetic as-built CAD digital twins. [PDF]

NPJ Metamater
Murchio S, De Biasi R, Laurenti M, Bonato N, Carmignato S, Benedetti M, Berto F.   +6 more
europepmc   +2 more sources

Reaction Mechanism, Challenges, and Strategies of High-Energy-Density Sodium-Ion Batteries. [PDF]

Adv Sci (Weinh)
Yu D, Cui Y, Chen Q, Gao L, Liu X, Li T, Zhu W, Li Q, Kang W.   +8 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

High-energy-density aqueous magnesium metal battery textiles enable ultrasensitive pressure sensing across -40° to 100°C. [PDF]

Sci Adv
Jia Y, Chen Y, Luo J, Bai Z, Li Q, Zhang Q.   +5 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Polycyclopropanated Lipid-Inspired Ionic Liquids as High Energy-Density Fuel Candidates. [PDF]

ACS Sustain Chem Eng
Butch CM, O'Brien RA, Jerdo RA, Davis JH, Zeller M, Rabideau BD, Hillesheim PC, Mirjafari A.   +7 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Challenges and advances of sulfide solid electrolytes for high-energy-density sodium metal batteries. [PDF]

Chem Sci
Chen K, Jiang H, Li H, Huang XL, Zhu K, Yao L, Lai W, Wang YX.   +7 more
europepmc   +1 more source