Results 131 to 140 of about 879,921 (312)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

IRS-Aided MIMO Spectrum Sensing via Alternating Phase Optimization

open access: yesIEEE Access
This paper investigates spectrum sensing in an intelligent reflecting surface (IRS)-assisted multiple-input multiple-output (MIMO) cognitive radio system. The objective is to enhance sensing performance by exploiting the passive beamforming capability of
Kuldeep Yadav   +2 more
doaj   +1 more source

Experimental Study on Fault Detection Algorithm Using Regression Method for Plural Indoor Units Faults of Multi-Heat Pump System under Heating Mode

open access: yes, 2012
This paper presents the fault detection algorithm using regression method for plural indoor units faults of multi-heat pump system under heating mode. To develop the fault detection algorithm, experiment was performed under no fault mode.
Kim, Hak Soo, Kim, Min Soo, Cho, Min Ki
core  

Transfer learning applications for anomaly detection in wind turbines

open access: yes
Anomaly detection in wind turbines typically involves using normal behaviour models to detect faults early. However, training autoencoder models for each turbine is time-consuming and resource intensive. Thus, transfer learning becomes essential for wind
Roelofs, Cyriana Maria Antonia   +3 more
core   +1 more source

Leak detection using instantaneous frequency analysis [PDF]

open access: yes, 2012
Leaking pipes are a primary concern for water utilities around the globe as they compose a major portion of losses. Contemporary interest surrounding leaks is well documented and there is a proliferation of leak detection techniques. Although the reasons
M. F., Ghazali, ghazali, mohd fairusham
core  

Free-Energy-Based Gene Mutation Detection Using LNA Probes

open access: yes, 2019
We have developed a label-free approach for direct detection of gene mutations using free-energy values that are derived from single-molecule force spectroscopy (SMFS)-based nucleic acid unbinding experiments.
Siddhartha Banerjee (1902061)   +2 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cooperative Detection Algorithm for Cognitive Radio Based on Relay Transmission

open access: yes工程科学与技术, 2011
:Aiming the degrading performance of cooperative detection for cognitive radio brought by the inaccurate detection of the cognitive users with low SNR, a cooperative detection algorithm in which the user with high SNR can transmit its detection ...
Liu Xin
doaj  

MLDCSS: Energy-Aware Multi-Level Cooperative Spectrum Sensing With Hierarchical Fusion and Non-Coherent MIMO in CR-IoT Networks

open access: yesIEEE Access
This research article presents a unique multi-level decision cooperative spectrum sensing (MLDCSS) framework for multiple-input-multiple-output (MIMO)-enabled cognitive radio internet of things (CR-IoT) networks.
Kaushik Das   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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