Results 171 to 180 of about 6,100,243 (291)

When Does Score Fusion Help? Conformally Certified Out-of-Distribution Detection for Camera and LiDAR Sensors. [PDF]

Sensors (Basel)
Szabó L, Weltsch Z, Ádámné-Major A.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Orchestrating agentic systems at ALS beamline 5.3.1 with Osprey and Bluesky. [PDF]

J Synchrotron Radiat
Chan KH, Ha Y, Islegen-Wojdyla A, Leon S, Garces M, McReynolds D, Chong X, Sriramoju RV, Mahl J, Guenzing D, Koepp W, Hexemer A, Hellert T, Chavez T.   +13 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Theoretical modeling and numerical simulation of a light-field detector for x-ray differential phase contrast imaging. [PDF]

Med Phys
Tan Y, Zhu J, Zhang X, Zheng H, Liang D, Ge Y.   +5 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Theoretical modeling and performance analysis of a direct-indirect dual-layer flat-panel detector for contrast-enhanced breast imaging. [PDF]

Med Phys
Wu X, Howansky A, Huang H, Duan X, Arnab SM, Gamache A, Warmoes P, Laperrière L, Zhao W.   +8 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Monte Carlo simulations of 241 Am α -particle energy distribution, LET distribution, and absorbed dose in a cell layer. [PDF]

Med Phys
Araszkiewicz M, Tymińska K, Kaźmierczak U, Chuchała P, Grzyb J, Kamińska P, Kwiatkowski R, Maleszewska M, Malinowska A, Maliszewska-Olejniczak K, Paterczyk B, Korgul A.   +11 more
europepmc   +1 more source